Adaptive tVNS Device with Closed-Loop Feedback Control

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Solution Overview

Problem

Conventional transcutaneous vagus nerve stimulation (tVNS) devices operate with a fixed stimulation protocol, failing to adapt to individual patient states or physiological rhythms, limiting treatment effectiveness.

Innovation Solution

A device equipped with sensors to detect real-time parameter values, such as heart rate or external factors, and a control unit to adjust stimulation pulse parameters, enabling adaptive tVNS based on detected values, including vital and external parameters, and allowing closed-loop feedback control.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a fixed stimulation protocol is used, then the device operation is simple and reliable, but the adaptability to individual patient needs and physiological states deteriorates

Engineering Contradiction:
Improvedevice operation reliabilityVSAvoidadaptability to patient needs
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent implements feedback control by detecting physiological parameters (such as heart rate, EEG signals, or other vital signs) and using this information to automatically adjust stimulation pulse parameters. The control unit continuously monitors the detected parameter values and modifies the stimulation protocol in real-time, creating a closed-loop system that adapts to the patient's current physiological state while maintaining reliable operation through automated control

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent transforms the static, fixed stimulation protocol into a dynamic system where stimulation parameters (amplitude, frequency, duration) can change in real-time based on detected physiological parameters. This dynamic adjustment allows the device to adapt to varying patient needs and physiological rhythms while maintaining operational reliability through structured control algorithms

Inventive Principle:
Principle #15Dynamics

2Adaptability or versatility

If stimulation parameters are adjusted based on detected parameter values, then the adaptability to individual patient states improves, but the device complexity increases

Engineering Contradiction:
Improveadaptability to physiological statesVSAvoiddevice structural complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent achieves adaptability by integrating multiple functions into a single control unit that can detect various physiological parameters and adjust multiple stimulation parameters based on a unified control algorithm. This multi-functional approach allows the device to adapt to different physiological states without proportionally increasing overall device complexity, as the control unit handles diverse functions through integrated processing

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The control unit serves as an intermediary between the detection means and the stimulation electrode, processing detected parameter values and translating them into appropriate stimulation adjustments. This intermediary layer simplifies the system architecture by centralizing the adaptation logic, preventing direct complex interactions between multiple sensors and stimulation parameters

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If real-time parameter detection and adjustment is implemented, then the treatment effectiveness improves, but the measurement and control difficulty increases

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidparameter measurement difficulty
Core Design Contradiction:
ReliabilityVSDifficulty of detecting and measuring

Solution Approach 1:

The patent uses feedback control where detected physiological parameters directly inform stimulation parameter adjustments, creating a closed-loop system that automatically compensates for measurement challenges. The control unit processes detected values and adjusts stimulation accordingly, reducing the need for manual interpretation and lowering the practical difficulty of real-time measurement and control

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system performs self-adjustment by automatically modifying stimulation parameters based on detected physiological states without requiring external intervention. The control unit autonomously processes measurement data and adjusts the stimulation protocol, enabling the device to self-optimize treatment effectiveness while reducing the operational burden of complex real-time measurements

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS12023494B2Device for performing a tVNS treatment
Publication Date: 2024.07.02 TVNS TECH GMBH

AI summary

The present invention relates to a device for performing a tVNS treatment having at least one electrode for generating a stimulation pulse, with the device having at least one detection means that is configured to detect one or more parameter values, and with the device having a control or regulation unit that is suitable to set one or more parameters of the stimulation pulse delivered by the electrode in dependence on the detected parameter value or values.