Adaptive Washing for Smear Preparation Apparatus
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
The existing smear preparation apparatuses face challenges in preventing carryover of abnormal blood cells during the processing of blood samples, which can lead to inaccurate diagnoses and increased processing time and reagent consumption, as they perform uniform washing operations for both healthy and patient samples.
Innovation Solution
A smear preparation apparatus with a blood processing unit and a washing unit that adjusts washing conditions based on the presence of abnormal blood cells, using a first and second washing condition, where the second condition is stronger when abnormal cells are detected, to effectively prevent carryover and optimize processing efficiency.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If uniform washing operation is performed for all blood samples, then carryover prevention is maintained, but processing time increases and reagent consumption increases
Solution Approach 1:
The patent applies local quality by differentiating washing operations based on sample characteristics. Normal washing is applied to samples without abnormal cells, while intensive washing is applied to samples containing abnormal cells like blasts. This selective approach ensures carryover prevention is maintained only where necessary, reducing unnecessary processing time and reagent consumption for normal samples.
Solution Approach 2:
The patent changes washing parameters (intensity, duration, reagent volume) based on the detection results of abnormal blood cells. When abnormal cells are detected, washing parameters are intensified; when normal samples are processed, standard parameters are used. This dynamic parameter adjustment resolves the contradiction by adapting washing strength to actual carryover risk.
2Reliability
If intensive washing operation is performed for all blood samples, then carryover prevention is improved, but reagent consumption increases and processing time increases
Solution Approach 1:
The patent applies local quality by differentiating washing operations based on sample characteristics. Normal washing is applied to samples without abnormal cells, while intensive washing is applied to samples containing abnormal cells like blasts. This selective approach ensures carryover prevention is maintained only where necessary, reducing unnecessary processing time and reagent consumption for normal samples.
Solution Approach 2:
The patent applies partial action by performing intensive washing only partially - specifically for samples containing abnormal cells - rather than universally for all samples. This partial intensive action maintains reliability where needed while avoiding excessive reagent consumption and processing time for normal samples.
3Reliability
If washing time is extended for all samples, then carryover prevention is improved, but processing power decreases
Solution Approach 1:
The patent applies local quality by differentiating washing operations based on sample characteristics. Normal washing is applied to samples without abnormal cells, while intensive washing is applied to samples containing abnormal cells like blasts. This selective approach ensures carryover prevention is maintained only where necessary, reducing unnecessary processing time and reagent consumption for normal samples.
Solution Approach 2:
The patent changes washing parameters (intensity, duration, reagent volume) based on the detection results of abnormal blood cells. When abnormal cells are detected, washing parameters are intensified; when normal samples are processed, standard parameters are used. This dynamic parameter adjustment resolves the contradiction by adapting washing strength to actual carryover risk.
Data Source
AI summary
A smear preparation apparatus comprises a blood processing unit, a washing unit, a controller, an information obtaining unit. The controller changes the washing condition for washing after processing a blood sample to a second washing condition which is stronger than the first washing condition when abnormal blood cells occur in the blood sample.