ADAQ3615 Corn Line for Marker-Assisted Regional Adaptation

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Solution Overview

Problem

Existing corn breeding methods struggle to develop inbred lines that are uniformly adapted across diverse regions of the U.S. Corn Belt, as hybrids often fail to address regional growing challenges such as Gray Leaf Spot, cool temperatures, Corn Lethal Necrosis, and soil pH issues, and lack a comprehensive agronomic package for broad adaptation.

Innovation Solution

Development of the maize variety ADAQ3615, which can be used to create inbreds and hybrids with specific traits, including resistance to diseases, improved agronomic characteristics, and tolerance to stress, using biotechnology techniques like microsatellites and SNPs to introduce desirable traits, and employing breeding methods like pedigree selection and backcrossing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional breeding methods are used to develop inbred lines, then breeding process is simpler, but the inbred lines lack uniform adaptation across diverse regions and fail to address regional challenges

Engineering Contradiction:
Improveadaptation to regional challengesVSAvoidbreeding process complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent employs molecular markers (microsatellites and SNPs) to detect and select specific genetic parameters associated with regional adaptation. By changing from phenotypic selection to genotypic selection based on marker parameters, the breeding process achieves uniform adaptation across diverse regions while maintaining systematic control over the complexity of the breeding program.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If hybrids are developed to address specific regional challenges, then regional adaptability improves, but the breeding program becomes too specialized for broad adaptation

Engineering Contradiction:
Improvebroad adaptationVSAvoidperformance consistency
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent develops inbred lines that serve multiple functions: they possess general adaptability for broad Corn Belt regions while simultaneously carrying specific genetic markers for regional challenge resistance. This multi-functional inbred line can be used in various hybrid combinations across different regions, achieving both broad adaptation and reliable regional performance consistency.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent introduces specific genetic traits (local quality) into inbred lines through marker-assisted selection, such as resistance to Gray Leaf Spot, Corn Lethal Necrosis, or tolerance to specific soil pH conditions. These localized adaptive traits are incorporated into otherwise broadly adapted inbred lines, enabling the same inbred to perform reliably across multiple regions with different challenges.

Inventive Principle:
Principle #3Local quality

3Productivity

If inbred lines are developed with comprehensive agronomic packages, then hybrid performance improves, but the development time and resource requirements increase

Engineering Contradiction:
Improvehybrid seed yieldVSAvoidbreeding program duration
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent performs preliminary identification and selection of desirable genetic traits using molecular markers before advancing lines through multi-year field trials. By pre-screening inbred lines for presence of key agronomic traits (disease resistance, stress tolerance, yield components) through DNA marker analysis, the program reduces the time required for phenotypic evaluation and accelerates the development of hybrids with comprehensive agronomic packages.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces traditional mechanical/phenotypic selection methods with molecular marker-based genotypic selection. Instead of visually evaluating and manually selecting plants based on physical traits over multiple growing seasons, the program uses DNA marker analysis to directly identify and select inbreds with desired agronomic traits, dramatically reducing the time and labor required to develop high-performing hybrids.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS12433220B2Variety corn line ADAQ3615
Publication Date: 2025.10.07 SYNGENTA CROP PROTECITON AG

AI summary

The present invention provides an inbred corn line designated ADAQ3615, methods for producing a corn plant by crossing plants of the inbred line ADAQ3615 with plants of another corn plant. The invention further encompasses all parts of inbred corn line ADAQ3615, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line ADAQ3615, and plants produced according to these methods.