Suppressing Discoloration in Adenosine Monophosphate and Tranexamic Acid Compositions
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Solution Overview
Problem
Compositions containing adenosine monophosphate and tranexamic acid tend to discolor over time, particularly yellowing, and also present a sticky feeling, which are issues that need to be addressed.
Innovation Solution
Incorporating specific chelating agents like tripolyphosphoric acid or its salts, metaphosphoric acid or its salts, etidronic acid or its salts, and pH adjusters such as organic alkali compounds, along with ingredients that suppress sticky feelings, to prevent discoloration and improve texture.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If adenosine monophosphate and tranexamic acid are blended in a composition, then whitening and skin improvement effects are achieved, but the composition discolors with time (yellowing)
Solution Approach 1:
The patent introduces a specific intermediary substance (vitamin C derivative) that acts as a mediator between the adenosine monophosphate/tranexamic acid mixture and the discoloration process. This intermediary prevents the direct interaction causing discoloration while maintaining the functional benefits of the active ingredients, thus resolving the contradiction between stability and effectiveness.
Solution Approach 2:
The patent changes the chemical parameters of the composition by introducing vitamin C derivatives and controlling pH levels. These parameter changes stabilize the composition by preventing oxidation and chemical reactions that lead to discoloration, while preserving the whitening and skin improvement effects of the main active ingredients.
2Reliability
If adenosine monophosphate is blended in a composition, then moisturizing and whitening effects are achieved, but the composition produces a sticky feeling
Solution Approach 1:
The patent creates a composite formulation by combining adenosine monophosphate with vitamin C derivatives and other compatible ingredients. This composite approach maintains the functional efficacy of the active ingredients while the combined formulation modifies the overall texture and reduces the sticky feeling, making the composition more acceptable for use.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively suppresses discoloration and sticky feelings, maintaining stability and usability over time.
Implementation Method 1
the present inventors have studied intensively to solve the above problem, and found that specific chelating agents and specific pH adjusters can respectively suppress the discoloration with time
Implementation Method 2
found that specific chelating agents and specific pH adjusters can respectively suppress the discoloration with time
Data Source
AI summary
The present disclosure provides a composition for external use comprising an adenosine phosphate and/or a salt thereof and tranexamic acid and/or a salt thereof, which further comprises a particular chelating agent and/or a pH adjuster that is an organic alkali compound.