Adiabatic Magnetization Preparation for B1 and B0 Insensitive MRI

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Solution Overview

Problem

Existing MRI systems face challenges in generating high contrast and signal-to-noise ratio images in inhomogeneous B1 and B0 fields, particularly in high field systems where current technologies are not cost-effective for providing uniform contrast.

Innovation Solution

The implementation of adiabatic magnetization preparation techniques, such as adiabatic inversion pulses, within the SWIFT (Sweep Imaging with Fourier Transform) sequence to generate T1 and T2 weighted images that are B1 insensitive, allowing for high contrast imaging in inhomogeneous environments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional magnetization preparation pulses are used in inhomogeneous B1 and B0 fields, then the imaging sequence is simple, but the image contrast and signal-to-noise ratio are inadequate

Engineering Contradiction:
Improveimage contrast and signal-to-noise ratioVSAvoidmagnetization preparation pulse complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies adiabatic inversion pulses with specific frequency and amplitude modulation parameters to achieve B1 and B0 insensitivity. The pulse parameters (frequency sweep, amplitude modulation) are optimized to compensate for field inhomogeneities, transforming the conventional approach into a field-insensitive one without significantly increasing operational complexity.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The adiabatic inversion pulse acts as an intermediary element between the non-ideal inhomogeneous fields and the desired uniform contrast imaging. This intermediate pulse sequence compensates for the harmful effects of B1 and B0 inhomogeneities, enabling high contrast images despite the presence of field variations.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If adiabatic inversion pulses are introduced to achieve B1 and B0 insensitivity, then image contrast improves, but the pulse sequence complexity increases

Engineering Contradiction:
Improveimage contrastVSAvoidpulse sequence complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The adiabatic inversion pulse is applied as a preliminary action before the main imaging sequence. This preparation pulse pre-compensates for field inhomogeneities by inverting magnetization in a controlled manner, setting up the conditions for subsequent uniform excitation and high contrast imaging without requiring complex real-time adjustments during data acquisition.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If high field MRI systems are used to improve resolution, then image quality improves, but acoustic noise increases requiring ear protection

Engineering Contradiction:
Improveimage resolutionVSAvoidacoustic noise
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent replaces conventional gradient-based excitation with adiabatic inversion pulses that rely on frequency-modulated RF fields. This substitution reduces the acoustic noise generated by rapid gradient switching, allowing high field MRI to be performed without requiring ear protection while maintaining high image resolution.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach results in high-resolution, clinically-quality images with improved signal-to-noise ratio and reduced motion artifacts, making it suitable for high field MRI systems without the need for ear protection due to lower acoustic noise levels, and effectively addresses the limitations of existing technologies in inhomogeneous field environments.

Implementation Method 1

Magnetization preparation entails delivering a preparatory pulse (or pulses) prior to data acquisition. These pulses are sometimes called MP-RAGE or IR-Prepared Fast SPGR.

Methodology Applied
Scientific EffectAdiabatic inversion:

Implementation Method 2

The present subject matter includes methods and systems for generating uniformly high contrast magnetic resonance (MR) images using inhomogeneous B1 and B0 fields.

Methodology Applied
Scientific EffectFrequency modulation: Phase Modulation

Implementation Method 3

SWIFT (Sweep Imaging with Fourier Transform) sequence to generate T1 and T2 weighted images

Methodology Applied
Scientific EffectSweep imaging:

Implementation Method 4

images generated using magnetic resonance can exhibit inadequate contrast or signal to noise ratio

Methodology Applied
Scientific EffectMagnetic resonance:

Data Source

PatentUS8502537B2Adiabatic magnetization preparation for B1 and B0 insensitive high contrast MRI
Publication Date: 2013.08.06 REGENTS OF THE UNIVERSITY OF MINNESOTA
  • US8502537B2 patent drawing
  • US8502537B2 patent drawing
  • US8502537B2 patent drawing

AI summary

A magnetic resonance image is produced by radial imaging using one or more preparatory pulses. The magnetic preparation pulse can include one or more adiabatic pulses.