Adipose Tissue Transfer System Pressure Control

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Solution Overview

Problem

Current adipose tissue reinjection systems lack real-time control and adjustment of pressure, leading to potential harm and injury to the recipient tissue due to excessive pressure during the transfer and reinjection process, which compromises the viability and safety of the adipose tissue.

Innovation Solution

A system equipped with a pressure sensor and reinjection pump that monitors and adjusts the internal pressure of the adipose tissue in real-time, interrupting the procedure when a predetermined pressure threshold is exceeded, and operates in a pulsed mode to ensure safe and efficient transfer of adipose tissue.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If real-time pressure monitoring and control systems are implemented, then the safety and viability of adipose tissue is improved, but the device complexity increases

Engineering Contradiction:
Improvesafety and viability of adipose tissueVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent implements real-time pressure monitoring through pressure sensors that continuously measure pressure during adipose tissue transfer. The system uses this feedback to automatically adjust pump operation, alert operators to abnormal conditions, and prevent harmful pressure levels that could damage tissue or cause embolism. This closed-loop feedback mechanism ensures tissue safety while maintaining manageable system complexity through automated control.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces manual mechanical pressure control with automated electronic pressure monitoring and control systems. Instead of relying on operators to manually regulate pressure through mechanical means, the system uses electronic sensors, microprocessors, and automated pump control to maintain pressure within safe parameters, thereby improving reliability while the automation manages the complexity burden.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Object-affected harmful factors

If pressure control mechanisms are added to the system, then the harm to recipient tissue is reduced, but the device complexity increases

Engineering Contradiction:
Improveharm to recipient tissueVSAvoiddevice complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

Real-time pressure sensors provide continuous feedback on pressure conditions at the injection site. The system automatically responds to pressure changes by adjusting pump operation or alerting operators, preventing harmful pressure levels that could cause tissue damage or fat embolism. This automated feedback loop reduces harm while managing complexity through intelligent control.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent introduces pressure sensors and control systems as intermediary components between the adipose tissue transfer process and the recipient tissue. These intermediaries monitor and regulate pressure conditions, acting as a protective buffer that prevents direct harmful effects on tissue while keeping the overall system complexity manageable through modular design.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Stability of the object's composition

If continuous monitoring of pressure and flow rate is implemented, then the viability of adipose tissue is maintained, but the device complexity increases

Engineering Contradiction:
Improveviability of adipose tissueVSAvoiddevice complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The system employs continuous real-time monitoring of both pressure and flow rate through integrated sensors. This feedback is processed by control systems that automatically adjust parameters to maintain optimal conditions for adipose tissue viability throughout the transfer and injection process, ensuring tissue stability and survival while managing system complexity through automated regulation.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent integrates multiple monitoring functions (pressure sensing, flow rate measurement, temperature monitoring) into a unified control system that manages all aspects of adipose tissue transfer. This multi-functional approach maintains tissue viability through comprehensive monitoring while reducing overall complexity by consolidating control functions into a single integrated system rather than separate independent devices.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively maintains the viability and safety of adipose tissue by controlling pressure and flow rates during the harvesting and reinjection process, reducing the risk of fat embolism and ensuring optimal tissue reinjection.

Implementation Method 1

a pressure sensor attached externally to a component of the system and configured to measure an internal pressure of the adipose tissue in the delivery channel

Methodology Applied
Scientific EffectPressure measurement:

Implementation Method 2

a reinjection pump structured to apply a positive-displacement pumping force to the delivery channel to cause a movement of the adipose tissue from the first end to the injection location

Methodology Applied
Scientific EffectPositive displacement pumping: Pump

Data Source

PatentUS10143811B2Fluid management of adipose tissue
Publication Date: 2018.12.04 WELLS JOHNSON CO
  • US10143811B2 patent drawing
  • US10143811B2 patent drawing
  • US10143811B2 patent drawing

AI summary

An adipose tissue (AT) transfer system includes, on the aspiration side, an aspiration cannula, an aspiration pump, a container, and flexible tubing connecting the aspiration cannula to the container. On the reinjection side, the system includes a reinjection cannula, flexible tubing connecting the inlet of the reinjection cannula to the container, and a reinjection pump imposing positive-displacement pumping action on the flexible tubing and causing movement of AT in a pulsed mode. The aspiration pump operates to continually supply harvested AT to the second flexible tubing while the reinjection pumps causes continuous or pulsed deposition of the AT at injection site. To ensure that internal pressure and/or flow of the AT through a channel of delivery of the AT to the reinjection site does not exceed a predetermined value, the system contains an external pressure sensor configured to measure such internal pressure in absence of a part that is in direct contact with the AT.