Adjustable Syringe Needle for Precise Dermal Injection

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Solution Overview

Problem

Existing syringes face challenges in uniformly injecting a small amount of vaccine into the epidermal layer of the skin due to individual variability in skin thickness, leading to potential leaks and inadequate immunity elicitation, as the needle length adjustment is insufficient to precisely target the dermal layer with a high concentration of immunocompetent cells.

Innovation Solution

A syringe design featuring an injection needle with a specific protruding length and blade face length, adjustable to ensure precise penetration into the dermal layer, minimizing leaks and effectively delivering a small vaccine dose to form a bulge near the epidermic layer in the dermic layer, regardless of age, gender, or individual differences.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a needle with fixed length is used for injection, then the device structure is simple, but it cannot adapt to individual variability in skin thickness and accurately target the dermal layer

Engineering Contradiction:
Improveinjection depth precisionVSAvoidneedle assembly structure
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The needle hub is designed with an adjusting portion that allows the needle tip protruding length to be modified. This dynamic adjustment capability enables the needle to adapt to different skin thicknesses and accurately reach the dermal layer containing immunocompetent cells, while maintaining a relatively simple overall structure through straightforward mechanical adjustment mechanisms.

Inventive Principle:
Principle #15Dynamics

2Manufacturing precision

If the needle tip protruding length is increased to reach the dermal layer, then injection accuracy improves, but the risk of vaccine leakage from the skin surface increases

Engineering Contradiction:
Improveinjection depth precisionVSAvoidvaccine containment
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The invention specifies optimal parameter ranges for the needle tip protruding length (0.5-1.5 mm) and blade face length (0.3-0.8 mm). These parameter optimizations ensure sufficient penetration depth to reach the dermal layer while maintaining adequate coverage to prevent vaccine leakage, balancing injection accuracy with containment reliability.

Inventive Principle:
Principle #35Parameter changes

3Strength

If a thicker needle is used for injection, then the needle strength and manufacturing convenience improve, but the ability to selectively inject into the thin epidermic layer decreases

Engineering Contradiction:
Improveneedle strengthVSAvoidinjection depth precision
Core Design Contradiction:
StrengthVSManufacturing precision

Solution Approach 1:

The needle is designed with differentiated local properties: the shaft maintains sufficient thickness for strength and handling, while the tip features a refined blade face with optimized dimensions (length 0.3-0.8 mm) for precise penetration into the thin epidermic layer. This local quality differentiation allows the needle to simultaneously satisfy mechanical strength requirements and fine precision injection requirements.

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS10413681B2Syringe for injecting drug solution into upper layer of skin
Publication Date: 2019.09.17 TERUMO KK
  • US10413681B2 patent drawing
  • US10413681B2 patent drawing
  • US10413681B2 patent drawing

AI summary

A syringe for injecting a drug solution into an upper layer of skin includes an injection needle having a needle hole communicating from a needle tip to a needle proximal end, the injection needle having a blade face at the needle tip; and a needle hub having a distal end portion and a proximal end portion, the needle hub holding the injection needle at the distal end portion. The needle hub has a needle tip side end face, and the needle tip protrudes from the needle tip side end face. A protruding needle length of the needle tip from the needle tip side end face is 1.15 mm±0.1 mm, and a blade face length of the blade face along an axis of the injection needle is 0.60 mm±0.15 mm.