Combustion-Driven Administration Apparatus Pressure Transition Control
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Solution Overview
Problem
Existing administration apparatuses, including needle-free injectors, often cause excessive load and damage to tissues and cells due to the high impact of drug solutions during administration, leading to invasiveness issues when penetrating the object region, particularly in the initial stages of administration.
Innovation Solution
An administration apparatus that utilizes a pressurization unit driven by combustion energy, with a specific pressure transition pattern involving a first vibration element followed by successive elements, to minimize invasiveness by controlling the pressure transition of the dosing liquid at the injection port, ensuring a converged state within a prescribed period, reducing damage to the object region.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Speed
If a drug solution is pressurized to inject into an object region using kinetic energy, then the drug solution can be administered to the desired depth, but the impact on the object region causes excessive load and damage to tissues and cells
Solution Approach 1:
The patent applies periodic action by controlling the pressure transition of the dosing liquid to include vibration elements with specific frequency characteristics. The pressure transition is designed to have a first vibration element followed by successive second, third, and fourth vibration elements, where the frequency and amplitude are controlled to reduce impact damage while maintaining injection effectiveness. This periodic pressure variation allows the dosing liquid to penetrate tissue more gently compared to a single high-impact pressure surge.
Solution Approach 2:
The patent employs dynamics by making the pressure transition adjustable and adaptive. The pressurization unit is configured to control the pressure transition according to specific criteria involving vibration elements and their frequency ratios. This dynamic control allows the system to optimize the pressure profile in real-time, balancing the need for sufficient injection depth with the need to minimize tissue damage. The pressure transition is not fixed but can be modified based on the desired injection parameters and tissue characteristics.
2Length of moving object
If high pressure is applied to penetrate the superficial layer and reach desired depth, then injection depth is achieved, but invasiveness to the object region increases
Solution Approach 1:
The patent uses periodic action to achieve injection depth while reducing invasiveness by employing a pressure transition with multiple vibration elements. The first vibration element helps penetrate the superficial layer, while the subsequent vibration elements with decreasing amplitude and specific frequency ratios continue the penetration process in a more gradual manner. This periodic pressure variation reduces the peak impact force compared to a single high-pressure surge, thereby reducing invasiveness while maintaining effective injection depth.
Solution Approach 2:
The patent applies parameter changes by controlling the frequency and amplitude characteristics of the pressure transition. The pressurization unit is designed to produce a pressure transition where the ratio of peak values between successive vibration elements falls within specific ranges. By adjusting these parameters (frequency ratios, amplitude decay rates), the system can optimize the balance between penetration depth and tissue invasiveness, adapting the pressure profile to different injection requirements and tissue types.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The apparatus effectively mitigates damage to the object region by controlling the pressure transition of the dosing liquid, allowing for efficient and minimally invasive administration of substances, such as vaccines and cultured cells, while maintaining the efficacy and functionality of the prescribed substance.
Implementation Method 1
a drive unit which imparts administration energy, wherein the drive unit comprises an igniter
Implementation Method 2
a pressurization unit comprising a piston configured to be pressurized by a combustion product generated by the igniter
Data Source
Figure 1
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Figure 2B
AI summary
Provided is an administration apparatus which administers a dosing liquid containing a prescribed substance to an object region, the administration apparatus including: a storage unit which stores the dosing liquid; a drive unit which imparts administration energy; a pressurization unit which pressurizes the dosing liquid stored in the storage unit with the administration energy in the drive unit; and an injection unit which injects the dosing liquid having been pressurized by the pressurization unit to the object region through an injection port. The pressurization unit pressurizes the dosing liquid so that, in an injection pressure transition of the dosing liquid corresponding to generation of administration energy, a vibration in the injection pressure transition reaches a converged state within a prescribed period of time from a rising time of pressure and, at the same time, a ratio of a peak value of an initial first vibration element in the vibration within the prescribed period of time to a peak value of subsequent vibration elements other than the first vibration element is higher than 1 and equal to or lower than a prescribed first ratio. As a result, invasiveness to the object region during administration is reduced.