Adsorption Column Tangential Inlet Flow Deceleration
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Solution Overview
Problem
Existing systems for the selective removal of molecules from bodily fluids are inadequate for addressing the removal of molecules from bodily fluids are inadequate for addressing the removal of molecules from bodily fluids are inadequate for addressing the removal of such molecules from bodily fluids are inadequate for addressing the removal of such molecules from bodily fluids are inadequate for addressing the removal of molecules from bodily fluids.
Innovation Solution
A cartridge system with a tangentially directed inlet and a conical end segment to decelerate bodily fluids before contact with adsorptive material, reducing chaotic flow and minimizing turbulence, thereby enhancing the removal of harmful molecules.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If bodily fluid is directed tangentially into the cartridge body at high speed, then the adsorption process can proceed quickly, but turbulence and chaotic flow increase causing platelet activation and fibrinogen deposition
Solution Approach 1:
The conical end segment is positioned before the adsorptive material to preliminarily decelerate and condition the bodily fluid flow before it contacts the adsorptive material. This preliminary action reduces flow velocity and turbulence intensity, preventing platelet activation and fibrinogen deposition while maintaining efficient adsorption throughput
Solution Approach 2:
The conical geometry of the end segment changes the flow parameters by progressively reducing flow velocity and transforming chaotic turbulent flow into more laminar flow patterns. This parameter change optimizes the flow conditions for adsorption while minimizing harmful effects on blood components
2Device complexity
If a straight inlet directly into the cartridge body is used, then the device complexity is reduced, but chaotic flow patterns and turbulence increase
Solution Approach 1:
The conical end segment introduces a curved, tapered geometry that guides flow smoothly into the cartridge body. This curved transition replaces abrupt straight-line flow paths, reducing flow separation and turbulence while maintaining relatively simple device construction
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively reduces platelet activation, fibrinogen deposition, and pressure increase, while improving the removal efficiency of harmful molecules from bodily fluids.
Implementation Method 1
the inlet is disposed tangential to the circular face at the cylindrical wall so as to direct bodily fluid entering the cartridge into the internal conical space tangentially so as to decelerate the bodily fluid within the internal conical space prior to contact with the adsorptive material
Implementation Method 2
a cartridge for the treatment of a bodily fluid may comprise a cartridge body configured to retain an adsorptive material
Data Source
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AI summary
Systems and methods for the treatment of a bodily fluid, for example, using a cartridge that may include a cartridge body configured to retain an adsorptive material and an end segment configured to cover a first end of the cartridge body. The end segment may include a circular face comprising an outwardly truncated conical shape and defining an internal conical space, a cylindrical wall joined to a periphery of the circular face, and an inlet configured to provide fluid connection to a source of the bodily fluid. The inlet may be disposed tangential to the circular face at the cylindrical wall so as to direct bodily fluid entering the cartridge into the internal conical space tangentially so as to decelerate the bodily fluid within the internal conical space prior to contact with the adsorptive material disposed within the cartridge body.