Anti-Pathogenic Aerosol Composition for Residue-Free Space Disinfection

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Solution Overview

Problem

Enclosed spaces pose a significant risk for the spread of pathogens such as bacteria and viruses, necessitating effective cleaning and decontamination methods.

Innovation Solution

An aerosol composition comprising ethanol, alkyldimethylbenzylammonium compound, and polyhexanide, optionally with a propellant, is used to disinfect surfaces and airborne pathogens, providing viricidal and bactericidal properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional disinfectants are used in enclosed spaces, then pathogen transmission is reduced, but residue left behind and potential harm to occupants occurs

Engineering Contradiction:

Improvepathogen inactivation effectivenessVSAvoidresidue and harm to occupants

Core Design Contradiction:

ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent modifies the chemical parameters of the disinfectant by formulating a specific combination of alcohol (ethanol or isopropanol) at 1-20% v/v, alkyldimethylbenzylammonium compound at 0.001-5% w/v, and polyhexanide at 0.005-10% w/v. This parameter optimization enables effective pathogen inactivation while minimizing harmful residues and improving safety for occupants in enclosed spaces.

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite disinfectant formulation by combining three different active ingredients: alcohol, alkyldimethylbenzylammonium compound, and polyhexanide. This composite approach synergistically enhances pathogen killing effectiveness while reducing the need for high concentrations of any single agent, thereby minimizing harmful residues.

Inventive Principle:

Principle #40Composite materials

2Area of stationary object

If aerosol dispensing is used for thorough coverage, then pathogen contact is improved, but fine particles may be inhaled by occupants

Engineering Contradiction:

Improvecoverage areaVSAvoidinhaled particles

Core Design Contradiction:

Area of stationary objectVSObject-affected harmful factors

Solution Approach 1:

The patent optimizes the aerosolization parameters by controlling the concentration of active ingredients and the physical properties of the formulation. The alcohol content (1-20% v/v) and the presence of polyhexanide modify the aerosol droplet size and evaporation rate, enabling thorough coverage while reducing the generation of respirable fine particles.

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent employs a disposable aerosol can formulation that delivers the disinfectant in a controlled manner. The formulation is designed to evaporate completely or leave minimal residue, effectively treating the enclosed space without requiring repeated applications or leaving persistent harmful particles.

Inventive Principle:

Principle #27Cheap short-living objects (Disposable)

3Reliability

If high concentrations of disinfectant are used, then pathogen killing effectiveness is improved, but safety for occupants and environmental harm increases

Engineering Contradiction:

Improvebactericidal and viricidal activityVSAvoidsafety and environmental harm

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent formulates a composite disinfectant with multiple active agents at optimized concentrations: alcohol (1-20% v/v), alkyldimethylbenzylammonium compound (0.001-5% w/v), and polyhexanide (0.005-10% w/v). This composite formulation achieves synergistic pathogen killing effectiveness at lower individual concentrations, reducing safety hazards and environmental harm compared to high-concentration single-agent formulations.

Inventive Principle:

Principle #40Composite materials

Solution Approach 2:

The patent optimizes the concentration parameters of each ingredient to achieve maximum disinfectant activity at the lowest effective doses. The specific ranges provided for alcohol, alkyldimethylbenzylammonium compound, and polyhexanide ensure sufficient pathogen inactivation while minimizing toxicity to occupants and environmental impact.

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively kills or inactivates a wide range of pathogens, including enveloped viruses and bacteria, without leaving residues, and can be dispensed as a fine aerosol for thorough coverage.

Implementation Method 1

an alkyldimethylbenzylammonium compound; polyhexanide... effectively kills or inactivates a wide range of pathogens, including enveloped viruses and bacteria

Methodology Applied

Scientific EffectCell membrane disruption:

Implementation Method 2

can be dispensed as a fine aerosol for thorough coverage... dispensing a composition of the first aspect as an aerosol into the space

Methodology Applied

Scientific EffectAerosolization: Aerosol

Implementation Method 3

When applied, the composition may leave no, or substantially no residue... The alcohol may be present in the composition in an amount between about 0.5% and about 20% (v/v)

Methodology Applied

Scientific EffectEvaporation: Evaporation

Data Source

PatentUS20250359545A1Anti-pathogenic aerosol compositions

Publication Date: 2025.11.27 SQUIRE KENT PTY LIMITED

AI summary

Disclosed herein is an anti-pathogenic aerosol composition comprising an alcohol selected from ethanol and isopropanol; an alkyldimethylbenzylammonium compound; polyhexanide; and water.