Aerosol-Generating Materials with Pre-Use Nitrite Reduction

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Solution Overview

Problem

Existing aerosol-generating products, such as heat-not-burn devices, generate harmful tobacco-specific nitrosamines (TSNAs) during the heating process due to the presence of nitrites in tobacco material, which react with amines to form these compounds.

Innovation Solution

Incorporation of a selectively releasable nitrite-decreasing additive, such as sorbic acid or ascorbic acid salts, into the aerosol-generating material or a separate chamber, which is released shortly before use to reduce nitrite levels and thereby decrease TSNA formation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If tobacco material is heated to generate aerosol, then aerosol is produced for inhalation, but harmful TSNAs are formed due to nitrite reactions

Engineering Contradiction:
Improveaerosol generationVSAvoidTSNA formation
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The nitrite-decreasing additive is incorporated into the aerosol-generating material in advance, positioned to contact the tobacco material shortly before heating. This preliminary action reduces nitrite levels proactively, preventing TSNA formation during the subsequent heating process while maintaining aerosol generation capability

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

A nitrite-decreasing additive acts as an intermediary substance between the tobacco material and the heating process. This additive selectively reduces nitrite content through chemical reaction or adsorption, thereby interrupting the pathway that leads to TSNA formation without interfering with the aerosol-generating properties of the tobacco material

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-generated harmful factors

If nitrite-decreasing additive is added to tobacco material, then TSNA formation is reduced, but additive stability and effectiveness are compromised over time

Engineering Contradiction:
ImproveTSNA reductionVSAvoidadditive stability
Core Design Contradiction:
Object-generated harmful factorsVSReliability

Solution Approach 1:

The additive is introduced to the tobacco material only shortly before use rather than being pre-mixed during manufacturing. This timing ensures the additive remains stable during storage and only becomes active when needed, maximizing both stability during storage and effectiveness at the moment of aerosol generation

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent specifies optimal concentration ranges for the nitrite-decreasing additive (0.01-5 wt%, preferably 0.05-3 wt%) to balance effectiveness in reducing TSNAs with stability during storage. This parameter optimization ensures the additive remains reliable throughout the product shelf life while maintaining sufficient activity to reduce TSNAs when activated

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The selective release of the nitrite-decreasing additive effectively reduces TSNA generation by up to 50% in the aerosol produced, ensuring a safer inhalation experience.

Implementation Method 1

aerosol-generating material comprising tobacco material and a selectively releasable source of a nitrite-decreasing additive... reduce nitrite levels and thereby decrease TSNA formation

Methodology Applied
Scientific EffectChemical reaction: Chemical Bonding

Implementation Method 2

the encapsulated nitrite-decreasing additive is released in a temperature-dependent manner... released upon being heated to a temperature within the range of from about 50°C to about 100°C

Methodology Applied
Scientific EffectTemperature-dependent release: Phase Change

Data Source

PatentEP4640078A1Aerosol-generating materials, consumables and aerosol provision systems
Publication Date: 2025.10.29 NICOVENTURES TRADING LTD
  • EP4640078A1 patent drawingFigure 1
  • EP4640078A1 patent drawingFigure 2
  • EP4640078A1 patent drawing

AI summary

The present invention relates to an aerosol-generating material comprising tobacco material and a selectively releasable source of a nitrite-decreasing additive. The invention also relates to consumables for use in an aerosol provision system, comprising an aerosol-generating material and a selectively releasable source of a nitrite-decreasing additive, as well as aerosol provision systems and uses of a selectively releasable source of a nitrite-decreasing additive to reduce the generation of tobacco-specific nitrosamines upon heating an aerosol-generating material.