Aerosolizable Material Turbidity Control
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Solution Overview
Problem
Aerosolizable materials containing cannabinoids often exhibit instability, leading to suboptimal performance and user perception of inferior quality due to high turbidity, which can result in inefficient constituent transfer and system performance issues.
Innovation Solution
Formulating an aerosolizable material with a cannabinoid and a carrier constituent, such as propylene glycol, to maintain a turbidity of 10 NTU or less, ensuring stability through specific concentration ratios and minimizing water content to prevent precipitation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If aerosolizable material is formulated with cannabinoid and carrier constituent, then the material can be used for aerosol delivery, but the material exhibits high turbidity leading to instability and suboptimal performance
Solution Approach 1:
The patent applies parameter changes by establishing specific concentration ranges for carrier constituents (propylene glycol at 60-90% w/w, glycerol at 5-30% w/w) and controlling cannabinoid content (0.1-20% w/w) to achieve turbidity of 10 NTU or less. This quantitative parameter optimization resolves the contradiction between formulation effectiveness and material stability.
Solution Approach 2:
The patent utilizes the solubility characteristics of carrier constituents at different temperatures by formulating the material to be heated during aerosol generation. The specific composition ensures optimal solubility and low turbidity when heated, transforming the physical state to achieve stable aerosol delivery while maintaining low turbidity in the liquid phase.
2Reliability
If the aerosolizable material is formulated to improve stability, then user acceptance improves, but requires specific concentration ratios and formulation constraints
Solution Approach 1:
The patent establishes specific concentration parameters (propylene glycol 60-90% w/w, glycerol 5-30% w/w, cannabinoid 0.1-20% w/w) that define the optimal formulation range. By providing these clear parameter boundaries, the patent simplifies the formulation process while ensuring stability and user acceptance, resolving the contradiction between reliability and formulation complexity.
3Quantity of substance
If high concentrations of cannabinoid are used, then the therapeutic effect is enhanced, but the turbidity increases leading to precipitation and instability
Solution Approach 1:
The patent uses carrier constituents (propylene glycol and glycerol) as intermediaries to solubilize cannabinoids. The specific ratio of carriers to cannabinoids (60-90% w/w propylene glycol, 5-30% w/w glycerol) acts as a mediating system that allows high cannabinoid concentrations (0.1-20% w/w) to remain dissolved without precipitation, resolving the contradiction between quantity and stability.
Solution Approach 2:
The patent creates a composite material system combining cannabinoid, propylene glycol, and glycerol in specific proportions. This composite formulation leverages the solubility properties of the carrier constituents to maintain high cannabinoid concentrations while preventing turbidity and precipitation, resolving the contradiction between substance quantity and stability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The formulation achieves stable aerosolizable materials with improved user acceptance and system performance by maintaining low turbidity and preventing cannabinoid precipitation, ensuring efficient constituent transfer and optimal system operation.
Implementation Method 1
an aerosolizable material is heated to form a vapor which is then allowed to condense into an aerosol
Implementation Method 2
an aerosolizable material is heated to form a vapor which is then allowed to condense into an aerosol
Implementation Method 3
subjecting the aerosolizable material to vibrations so as to form small particles of material that are entrained in airflow
Data Source
AI summary
An aerosolizable material is provided. The aerosolizable material comprises at least one cannabinoid, and at least one carrier constituent, the material having a turbidity of about 10 NTU or less. Methods of making the aerosolizable material and articles comprising the aerosolizable material are also provided.

