Atrial Fibrillation Detection With Ventricular Pacing Adjustment

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Solution Overview

Problem

Current implantable medical devices (IMDs) face challenges in detecting atrial fibrillation (AF) due to the interference of ventricular pacing, leading to under-detection, especially when ventricular rates fall below the detection cutoff, and conventional AF detection algorithms are not suitable for single-chamber IMDs that deliver pacing therapy.

Innovation Solution

A computer-implemented method and system that analyze far-field cardiac activity signals to identify paced events, calculate pacing incidence scores, and adjust AF detection parameters to improve the detection of atrial fibrillation by accounting for ventricular pacing incidents, thereby enhancing the accuracy of AF detection in the presence of pacing events.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If ventricular pacing is delivered by a single-chamber IMD, then ventricular rate control is improved, but AF detection accuracy deteriorates due to reduced R-R interval variability

Engineering Contradiction:
Improveventricular rate controlVSAvoidAF detection accuracy
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent dynamically adjusts the AF detection algorithm based on the detected pacing mode and rate. When ventricular pacing is detected, the system switches from conventional R-R variability analysis to alternative detection methods that account for the suppressed variability, thereby maintaining AF detection accuracy despite the dynamic changes in cardiac rhythm control

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes the detection parameters and criteria when ventricular pacing is present. Instead of using fixed thresholds for R-R interval variability, the system adapts the detection parameters to account for the reduced variability caused by pacing, enabling accurate AF detection under different physiological conditions

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If conventional AF detection algorithms based on R-R interval variability are used, then AF detection is effective in natural rhythm, but detection fails when ventricular pacing suppresses R-R variability

Engineering Contradiction:
ImproveAF detection sensitivityVSAvoiddetection algorithm compatibility
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The patent creates a universal AF detection system that can operate effectively in multiple cardiac rhythm conditions - both natural sinus rhythm and ventricular pacing modes. The detection algorithm automatically adapts its methodology based on the detected pacing state, making it versatile enough to handle different physiological conditions without requiring separate dedicated algorithms

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If ventricular rate falls below detection cutoff, then pacing therapy is maintained, but AF under-detection occurs

Engineering Contradiction:
Improvepacing therapy deliveryVSAvoidAF detection rate
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent performs preliminary analysis of the cardiac rhythm characteristics and pacing incidence before finalizing the AF detection decision. By proactively identifying patterns consistent with AF in the presence of low-rate ventricular pacing, the system can detect AF episodes that would otherwise fall below conventional detection thresholds, ensuring timely therapy delivery

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS10966650B2Method and device for detecting atrial fibrillation in the presence of ventricular pacing
Publication Date: 2021.04.06 PACESETTER INC
  • US10966650B2 patent drawing
  • US10966650B2 patent drawing
  • US10966650B2 patent drawing

AI summary

Methods and systems are provided for detecting arrhythmias in cardiac activity is provided. The method and systems are under control of one or more processors configured with specific executable instructions. The method and systems obtain a far field cardiac activity (CA) signal that includes a series of beats, the CA signal including paced events. The method and systems identify the paced events in the CA signals. The method and systems determine a score based on an amount of paced events and adjust at least one parameter of an atrial fibrillation (AF) detection process based on the score.