Atrial Fibrillation Mapping via Finite Element Model and Neural Network

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Solution Overview

Problem

Current methods for treating atrial fibrillation lack precision and predictability due to the absence of a reliable methodology for analyzing and mapping the condition, making catheter ablation procedures less effective.

Innovation Solution

A system utilizing a finite element model (FEM) of the heart, combined with electrogram data and an artificial neural network (ANN), to generate function parameters that enable precise identification and characterization of atrial fibrillation, predicting occurrences, and determining appropriate treatments such as drug delivery and ablation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If catheter ablation is used to treat atrial fibrillation, then treatment can be applied to terminate the arrhythmia, but the procedure lacks precision and predictability due to absence of accurate analysis methodology

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidAF analysis precision
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The heart is divided into multiple discrete elements within a finite element model, allowing individual analysis of each element's electrophysiological properties. This segmentation enables precise localization of abnormal electrical activity and facilitates targeted ablation therapy by treating specific elements rather than large areas.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system calculates multiple function parameters for each FEM element, including activation time, dominant frequency, and AF burden. These parameter changes transform raw electrogram data into quantifiable metrics that enable precise characterization of AF and guide treatment decisions with improved reliability.

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If traditional catheter ablation procedures are performed based on doctor judgment, then treatment can be delivered, but the procedure is not precise or predictable

Engineering Contradiction:
Improveprocedure simplicityVSAvoidablation location precision
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

An artificial neural network serves as an intermediary between raw electrogram data and treatment decisions. The ANN automatically processes complex electrogram signals and calculates function parameters, eliminating the need for complex manual analysis while providing precise, objective guidance for ablation location and energy delivery.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system replaces subjective doctor judgment with an automated computational approach using finite element modeling and artificial neural networks. This substitution transforms the procedure from a manual, judgment-based process to an automated, data-driven system that provides precise and predictable ablation guidance.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Loss of time

If no accurate methodology is used to determine ablation parameters, then treatment can proceed without complex analysis, but the procedure lacks predictability

Engineering Contradiction:
Improveanalysis timeVSAvoidtreatment predictability
Core Design Contradiction:
Loss of timeVSReliability

Solution Approach 1:

The system performs preliminary calculation of function parameters for all FEM elements before ablation begins. By pre-calculating activation times, dominant frequencies, and AF burden for each element, the system establishes a complete treatment map in advance, enabling predictable and systematic ablation delivery without time-consuming intra-procedural analysis.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS7715907B2Method and system for atrial fibrillation analysis, characterization, and mapping
Publication Date: 2010.05.11 SIEMENS HEALTHINEERS AG
  • US7715907B2 patent drawing
  • US7715907B2 patent drawing
  • US7715907B2 patent drawing

AI summary

A method and system for atrial fibrillation analysis, characterization, and mapping is disclosed. A finite element model (FEM) representing a physical structure of a heart is generated. Electrogram data can be sensed at various locations in the heart using an electrophysiology catheter, and the electrogram data is mapped to the elements of the FEM. Function parameters, which measure some characteristics of AF arrhythmia, are then simultaneously calculated for all of the elements of the FEM based on the electrogram data mapped to the elements of the FEM. An artificial neural network (ANN) can be used to calculate the function parameters.