Plant-Based Soft Gel Capsule Films Using Agar and Starch

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Solution Overview

Problem

There is a need for film-forming compositions that do not use gelatin or carrageenans for making soft gel capsules, as gelatin raises ethical and health concerns, and carrageenan-based films can cause inflammation-related side effects.

Innovation Solution

The development of film-forming compositions comprising 1-60% hydroxyalkylated plant starch or plant sugar, 1-30% agar, and 30-80% water, which are used to create soft gel capsules without gelatin or carrageenans, reducing cracking and sticking issues during storage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If gelatin is used to make soft gel capsules, then the capsules can be formed effectively, but ethical and health concerns arise due to animal origin and potential prion contamination

Engineering Contradiction:
Improvecapsule formation reliabilityVSAvoidethical and health concerns
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and eliminates gelatin from the capsule formulation, replacing it with plant-based alternatives (pectin, agar, or alginate combined with starch). This removal of the problematic animal-derived ingredient resolves the ethical and health concerns while maintaining capsule formation capability through the alternative hydrocolloid-starch composite system.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the material composition parameters by substituting gelatin with specific plant-based hydrocolloids and starch combinations. By adjusting the ratios of pectin/agar/alginate with starch (within specified ranges), the formulation achieves comparable functional properties without animal-derived ingredients, thus resolving the contradiction between reliability and harmful factors.

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If carrageenan is used as a gelatin replacement, then animal product concerns are addressed, but inflammation-related side effects occur

Engineering Contradiction:
Improveanimal product concernsVSAvoidinflammation-related side effects
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent removes carrageenan from the formulation entirely, offering alternative plant-based hydrocolloids (pectin, agar, or alginate) combined with starch. This extraction eliminates the inflammation-related harmful effects associated with carrageenan while still addressing the original need to avoid animal products.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs commonly available plant-based materials (pectin from fruits, agar from algae, alginate from seaweed) combined with starch, which are generally recognized as safe and have established safety profiles. These materials provide a safe, inflammation-free alternative to carrageenan while maintaining capsule functionality.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Object-affected harmful factors

If alternative plant-based materials are used without gelatin or carrageenan, then ethical and health concerns are resolved, but cracking and sticking issues may arise during storage

Engineering Contradiction:
Improveethical and health concernsVSAvoidstorage stability
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent employs composite material formulations combining plant-based hydrocolloids (pectin, agar, or alginate) with starch in specific ratios. This composite approach leverages the complementary properties of each component: the hydrocolloids provide gel structure and flexibility, while starch contributes to structural integrity and reduces cracking and sticking during storage, thus resolving the reliability issue.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent optimizes the compositional parameters by specifying precise weight ratio ranges for the hydrocolloid-to-starch combination. By adjusting these parameters within the defined ranges, the formulation achieves optimal balance between flexibility and structural integrity, preventing both cracking and sticking during storage while maintaining the plant-based, gelatin-free composition.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The proposed compositions effectively encapsulate fill materials with low cracking and sticking, providing a suitable alternative for soft gel capsules that are free from animal-derived products and carrageenan-related inflammation concerns.

Implementation Method 1

hydroxyalkylated plant starch, a plant sugar, or a combination thereof; (b) from 1 to 30 percent by weight agar

Methodology Applied
Scientific EffectGelation: Gel

Implementation Method 2

film-forming compositions, the compositions comprising: (a) from 1 to 60 percent by weight of a hydroxyalkylated plant starch, a plant sugar, or a combination thereof

Methodology Applied
Scientific EffectFilm-forming:

Data Source

PatentUS20240415779A1Soft gel compositions and capsules made from the same
Publication Date: 2024.12.19 CAPTEK SOFTGEL INTERNATIONAL INC
  • US20240415779A1 patent drawing

AI summary

Film-forming compositions for soft capsule formation have from 2 to 20 percent by weight of a mixture of hydroxyalkylated plant starch and a plant sugar, from 15 to 25 percent by weight agar, no more than 5 percent by weight gelatin, no more than 1 percent by weight carrageenan, and water as the balance thereof. Soft capsules made from such a film-forming composition and methods of making the same are also disclosed.