AI Cell Analysis Method Resolving Ambiguous Classification

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing AI algorithms struggle with accurately classifying cells when the probability of belonging to multiple types is similar, leading to decreased classification accuracy.

Innovation Solution

The method involves obtaining optical signals from a specimen using a measurement unit and analyzing set data using an artificial intelligence algorithm that calculates the relevance degree between different pieces of data to determine the type of analyte, thereby improving classification accuracy by distinguishing between ambiguous cell types.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If an AI algorithm individually analyzes features of each cell to determine cell type, then the analysis can handle complex cell characteristics, but the classification accuracy decreases when multiple types have similar probabilities

Engineering Contradiction:
Improveability to analyze complex cell characteristicsVSAvoidcell type classification accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent segments the cell analysis process into two distinct stages: first extracting individual cell features using AI algorithms, then performing pairwise comparisons between cells to resolve ambiguous classifications. This segmentation allows the system to maintain the ability to analyze complex characteristics while improving classification accuracy through the additional comparison stage.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent implements a feedback mechanism where the classification results from individual cell analysis are used to generate reference information, which then feeds back into the pairwise comparison process. This feedback loop enables the system to refine and improve classification accuracy by using previously determined classifications to resolve ambiguities in subsequent comparisons.

Inventive Principle:
Principle #23Feedback

2Loss of information

If the AI algorithm outputs probability values for multiple cell types, then the analysis provides comprehensive type information, but it creates ambiguity when probabilities are similar and reduces identification reliability

Engineering Contradiction:
Improvecompleteness of type informationVSAvoidcell type identification reliability
Core Design Contradiction:
Loss of informationVSReliability

Solution Approach 1:

The patent extracts the probability values and type information from individual cell analyses and uses them as reference information for pairwise comparisons. By taking out this information and using it in a systematic comparison process, the system maintains comprehensive type information while resolving ambiguities through structured comparison of multiple cells.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent adds a new dimension to the analysis by introducing pairwise comparisons between cells as a third level of processing, beyond individual feature analysis and probability calculation. This dimensional extension allows the system to resolve ambiguities in cell type identification by considering relationships between multiple cells simultaneously.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentUS20240331814A1Analysis method, specimen analyzer, and program
Publication Date: 2024.10.03 SYSMEX CORP
  • US20240331814A1 patent drawing
  • US20240331814A1 patent drawing
  • US20240331814A1 patent drawing

AI summary

Disclosed is an analysis method for analyzing an analyte in a specimen, the analysis method including: obtaining first data corresponding to an optical signal obtained from the analyte; inputting set data composed of a plurality of pieces of the first data, to an artificial intelligence algorithm capable of calculating a relevance degree between the pieces of the first data; and determining a type of the analyte by using the relevance degree.