AI Hemodynamic Prediction from Noninvasive Biosignals

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Solution Overview

Problem

Current hemodynamic monitoring relies heavily on invasive methods for accurate measurements of parameters like pulmonary arterial pressure, central venous pressure, and arterial blood pressure, which can be cumbersome and less accessible for continuous, non-invasive monitoring.

Innovation Solution

An apparatus and method utilizing non-invasive biosignals and AI models to predict hemodynamic parameters, such as pulmonary arterial pressure, arterial blood pressure, and central venous pressure, from input variables like ECG, ICG, PPG, and other general inputs, allowing for non-invasive estimation of these parameters using a processor and AI analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If invasive sensors or catheters are used to measure hemodynamic parameters, then measurement precision is improved, but device complexity and patient discomfort increase

Engineering Contradiction:
Improvehemodynamic parameter measurement accuracyVSAvoidinvasive sensor implantation complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent uses an AI model as an intermediary to translate easily obtainable noninvasive biosignals (ECG, PPG, ICG) into accurate predictions of hemodynamic parameters. This mediator enables the system to achieve clinical-grade measurement precision without requiring direct invasive contact with blood vessels or heart chambers.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention replaces the mechanical invasive catheter-based measurement system with a computational approach using AI models that process electrical and optical biosignals. This substitution eliminates the need for physical insertion of sensors into the cardiovascular system while maintaining measurement accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If invasive catheters are used for continuous hemodynamic monitoring, then measurement reliability is improved, but ease of operation deteriorates

Engineering Contradiction:
Improvecontinuous hemodynamic monitoring reliabilityVSAvoidmonitoring system accessibility
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The system utilizes biosignals that are naturally produced by the patient's own physiology (electrical signals from the heart, optical signals from blood flow) and processes them through AI algorithms. This self-service approach eliminates the need for external invasive instrumentation while maintaining continuous monitoring capability.

Inventive Principle:
Principle #25Self-service

3Ease of operation

If noninvasive methods are used to estimate hemodynamic parameters, then ease of operation is improved, but measurement precision deteriorates

Engineering Contradiction:
Improvenoninvasive monitoring accessibilityVSAvoidhemodynamic parameter estimation accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent transforms the relationship between input biosignals and output hemodynamic parameters through AI model processing. By changing the analytical parameters and using sophisticated algorithms, the system achieves clinical-grade precision from noninvasive measurements, overcoming the traditional accuracy limitations of such methods.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20230210471A1Assessment of Hemodynamics Parameters
Publication Date: 2023.07.06 SILVERLEAF MEDICAL SCIENCES INC
  • US20230210471A1 patent drawing
  • US20230210471A1 patent drawing
  • US20230210471A1 patent drawing

AI summary

The present disclosure relates to an apparatus for predicting a hemodynamics parameter being conventionally obtained from an implanted sensor or catheter (invasive sensor), e.g., pulmonary artery pressure, based on noninvasive biosignals, such as electrocardiographic (ECG), impedance cardio graphic (ICG), phonocardiogram (PCG), pulse oximetry plethysmograph (PPG). The present disclosure also relates to a method of feeding multiple noninvasive biosignals and/or general inputs into an AI model or AI models to predict a hemodynamics parameter, such as pulmonary artery pressure, which is conventionally obtained from an implanted sensor or catheter.