AI-Powered Digital Pathology Slide Navigation System

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Solution Overview

Problem

Pathologists face inefficiencies and fatigue when manually reviewing digital pathology slides due to the need for extensive panning and zooming across large images, which can lead to prolonged diagnostic review times and physical strain.

Innovation Solution

The implementation of a system that uses artificial intelligence to automatically determine the presence of clinical features and apply policies for smoothly navigating through salient regions of interest, allowing for automatic panning and zooming based on tissue type, findings, and user objectives, thereby reducing the need for manual input and minimizing fatigue.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If pathologists manually review digital pathology slides by panning and zooming, then they can examine tissue details, but diagnostic review time increases and physical strain occurs

Engineering Contradiction:
Improvetissue examination accuracyVSAvoiddiagnostic review time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary analysis by automatically detecting and identifying salient regions of interest in the pathology slide before the pathologist begins review. This pre-processing step highlights critical areas, allowing the pathologist to directly navigate to relevant regions rather than manually searching through the entire slide, thus reducing review time while maintaining examination accuracy

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system replaces the manual mechanical panning and zooming operations with an automated computer-controlled navigation system. The computer automatically pans and zooms to salient regions based on detected features, substituting the pathologist's manual mechanical interactions with an automated digital navigation system that can rapidly move between regions of interest

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Loss of information

If pathologists manually pan and zoom across large images, then they can locate salient regions, but physical strain and fatigue increase

Engineering Contradiction:
Improvesalient region detection completenessVSAvoidpathologist fatigue and eye strain
Core Design Contradiction:
Loss of informationVSObject-affected harmful factors

Solution Approach 1:

The system enables self-service by automatically detecting, identifying, and navigating to salient regions without requiring continuous manual intervention from the pathologist. The computer vision system independently performs region detection and navigation, allowing the pathologist to review findings without the physical strain of manual panning and zooming operations

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system substitutes the pathologist's manual mechanical panning and zooming operations with an automated computer-controlled navigation system. This replacement eliminates the physical strain and eye strain associated with prolonged manual operation while maintaining complete detection of salient regions through automated image analysis

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If automatic panning is implemented across multiple images, then navigation efficiency improves, but system complexity increases

Engineering Contradiction:
Improvenavigation efficiencyVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system segments the navigation task into distinct functional modules: salient region detection, region identification, priority ordering, and automated panning control. Each module handles a specific aspect of the navigation process, allowing the complex overall task to be managed through modular, independently optimized components that improve navigation efficiency while keeping system complexity manageable

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS12182996B2Systems and methods to process electronic images to identify attributes
Publication Date: 2024.12.31 PAIGE AI INC
  • US12182996B2 patent drawing
  • US12182996B2 patent drawing
  • US12182996B2 patent drawing

AI summary

A computer-implemented method may identify attributes of electronic images and display the attributes. The method may include receiving one or more electronic medical images associated with a pathology specimen, determining a plurality of salient regions within the one or more electronic medical images, determining a predetermined order of the plurality of salient regions, and automatically panning, using a display, across the one or more salient regions according to the predetermined order.