AI Model for Radiation Therapy Dose Distribution Prediction

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Solution Overview

Problem

Current methods for optimizing radiation therapy treatment plans are inefficient and heavily reliant on subjective medical expertise, leading to time-consuming and suboptimal results in achieving desired dose distributions for cancer treatment.

Innovation Solution

An automated system utilizing an artificial intelligence model trained on historical radiation therapy data to predict and visualize dose distributions, allowing for objective optimization of treatment plans and reducing reliance on manual adjustments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional manual optimization methods are used to determine radiation parameters, then treatment plans can be customized based on medical professional expertise, but the process becomes time-consuming and inefficient

Engineering Contradiction:
Improveaccuracy of treatment planVSAvoidcalculation time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system pre-calculates and stores dose distribution data for multiple radiation parameters before actual treatment planning. When a treatment plan is needed, the system retrieves pre-computed data instead of calculating from scratch, significantly reducing calculation time while maintaining accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system uses machine learning models trained on historical treatment data to predict dose distributions for new cases. These models learn from patterns in previously optimized treatment plans and replicate successful strategies, providing accurate predictions without requiring time-consuming manual optimization for each new patient.

Inventive Principle:
Principle #26Copying

2Reliability

If multiple simulations are run to optimize radiation parameters, then better dose distribution can be achieved, but the process becomes tedious and complex

Engineering Contradiction:
Improvequality of dose distributionVSAvoidcomplexity of optimization process
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system automatically performs the optimization process using machine learning models that self-adjust parameters based on learned patterns from training data. The system serves itself by making intelligent predictions without requiring manual intervention to run multiple simulations or adjust parameters iteratively.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system transforms the complex optimization problem into a parameter prediction task. Instead of running multiple simulations to explore parameter space, the machine learning model directly predicts optimal parameters based on input features, simplifying the process while maintaining reliability.

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If conventional methods rely on medical professional subjective knowledge, then treatment plans can be customized, but the results depend on individual expertise and may not be optimal

Engineering Contradiction:
Improvecustomization capabilityVSAvoidconsistency of results
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The machine learning model serves multiple functions: it predicts dose distributions, suggests optimal radiation parameters, and provides treatment plan recommendations. This universal system replaces multiple specialized tools and expert knowledge bases with a single integrated solution that maintains consistency across different users and cases.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS12053646B2Artificial intelligence modeling for radiation therapy dose distribution analysis
Publication Date: 2024.08.06 SIEMENS HEALTHINEERS INTERNATIONAL AG
  • US12053646B2 patent drawing
  • US12053646B2 patent drawing
  • US12053646B2 patent drawing

AI summary

Disclosed herein are methods and systems to optimize a radiation therapy treatment plan using dose distribution values predicted via a trained artificial intelligence model. A server trains the AI model using a training dataset comprising data associated with a plurality of previously implemented radiation therapy treatments on a plurality of previous patients and dose distributions associated with one or more organs of each previous patient. The server then executes the trained AI model to predict dose distribution for a patient. The server then displays a heat map illustrating the predicted values, transmits the predicted values to a plan optimizer to generate an optimized treatment plan for the patient, and/or transmits an alert when a treatment plan generated by a plan optimizer deviates from rules and thresholds indicated within the patient's plan objectives.