AI Response Evaluation via Domain-Specific and Agnostic Guidance

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Solution Overview

Problem

There is a need to evaluate the quality, accuracy, and safety of responses generated by AI large language models like ChatGPT for patient-related questions in radiation oncology, as existing technologies lack comprehensive methods for assessing these aspects.

Innovation Solution

A method is introduced that combines domain-specific and domain-agnostic evaluations to assess the quality of ChatGPT-generated responses. This involves generating responses to patient queries, performing domain-specific evaluations using expert guidance, and domain-agnostic evaluations through statistical analysis, to provide a comprehensive assessment of response accuracy, completeness, and potential harm.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If AI large language models are used to generate responses for patient questions, then efficiency and accessibility are improved, but reliability and accuracy deteriorate due to hallucinations and factually inaccurate responses

Engineering Contradiction:
Improveresponse efficiencyVSAvoidresponse accuracy
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent introduces an intermediary evaluation system that acts as a mediator between the AI model and the final response. This system includes domain-specific evaluators (medical experts, fact-checking systems) and domain-agnostic evaluators (readability, bias detection) that verify and validate AI-generated responses before they reach patients, thus resolving the contradiction between efficiency and reliability

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent implements a feedback mechanism where AI-generated responses are evaluated by multiple evaluators and the results are used to improve future responses. The system continuously learns from evaluation feedback, adjusting its response generation process to reduce hallucinations and improve accuracy while maintaining efficiency

Inventive Principle:
Principle #23Feedback

2Reliability

If comprehensive evaluation methods are implemented for AI responses, then reliability is improved, but device complexity and evaluation time increase

Engineering Contradiction:
Improveresponse qualityVSAvoidevaluation system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the evaluation system into distinct modular components: domain-specific evaluators (medical accuracy, fact-checking) and domain-agnostic evaluators (readability, bias, sensitivity). Each module performs a specific evaluation function independently, making the complex evaluation process manageable, maintainable, and scalable while ensuring comprehensive response quality assessment

Inventive Principle:
Principle #1Segmentation

3Measurement precision

If domain-specific evaluation using expert guidance is used, then measurement precision is improved, but loss of time increases due to manual review processes

Engineering Contradiction:
Improveevaluation accuracyVSAvoidevaluation time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs preliminary automated evaluations using domain-specific algorithms and fact-checking systems before human expert review. This preliminary action filters out obviously incorrect responses and prepares evaluation materials in advance, allowing human experts to focus only on complex cases that require their specialized judgment, thus reducing overall evaluation time while maintaining high precision

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250053791A1Method to evaluate and fact-check an ai large language model chat response using domain- specific and domain-agnostic guidance for personalized medical provider-patient consult
Publication Date: 2025.02.13 NORTHWESTERN UNIV
  • US20250053791A1 patent drawing
  • US20250053791A1 patent drawing
  • US20250053791A1 patent drawing

AI summary

A method for evaluating an artificial intelligence (AI) large language model (LLM) generated response, the method comprising receiving a user query in the form of patient-related questions for a medical treatment domain; analyzing the user query using a LLM learned with open-source data and outputting a LLM answer from the LLM; performing a domain-specific evaluation of the LLM answer; performing a domain-agnostic evaluation of the LLM answer; generating at least one metric for the LLM answer based on the domain-specific evaluation and the domain-agnostic evaluation of the LLM answer; and evaluating the quality of the LLM answer based on the at least one metric.