AI Transfusion Decision Support System

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Solution Overview

Problem

Current blood transfusion management systems lack the ability to account for individual patient variables, leading to inappropriate transfusions and increased risks of adverse side effects, and they lack transparency and traceability, resulting in higher mortality, morbidity, and healthcare complications.

Innovation Solution

A computer-implemented system using artificial intelligence (AI) and machine learning (ML) technologies to determine the appropriateness of blood transfusions by analyzing patient-specific data, historical transfusion data, and domain knowledge, providing a transfusion appropriateness score and recommending the type, amount, and timing of blood products, while also tracking and reporting transfusion procedures for improved decision-making and resource management.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If physician discretion is used to determine transfusion candidates, then ease of operation is improved, but manufacturing precision deteriorates

Engineering Contradiction:
Improveease of operationVSAvoidtransfusion appropriateness
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent replaces the mechanical system of human physician discretion with an automated AI-based decision support system that processes patient data, medical history, and clinical parameters to generate transfusion recommendations, thereby substituting human judgment with algorithmic precision

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system changes the parameters of transfusion decision-making by incorporating multiple quantifiable factors including patient-specific variables, laboratory values, comorbidities, and risk stratification criteria into a structured analytical framework that produces objective appropriateness scores

Inventive Principle:
Principle #35Parameter changes

2Reliability

If current blood management systems are used, then device complexity is reduced, but reliability deteriorates

Engineering Contradiction:
Improvetransfusion safetyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent creates a multi-functional system that simultaneously performs patient identification, risk assessment, appropriateness scoring, recommendation generation, and tracking functions within a single integrated platform, making the system universally applicable across different transfusion scenarios

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The AI-based decision support system acts as an intermediary between available patient data and clinical transfusion decisions, processing and analyzing multiple data sources to generate evidence-based recommendations that bridge the gap between raw data and clinical action

Inventive Principle:
Principle #24Intermediary (Mediator)

3Object-affected harmful factors

If individual patient variables are not accounted for, then device complexity is reduced, but object-affected harmful factors increase

Engineering Contradiction:
Improveadverse side effectsVSAvoidsystem complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent applies local quality by tailoring the transfusion assessment to each individual patient's specific characteristics, medical history, comorbidities, and clinical parameters, ensuring that the analysis is customized to the unique needs and risks of each patient rather than applying uniform criteria

Inventive Principle:
Principle #3Local quality

4Loss of information

If current blood management systems are used, then loss of substance is reduced, but loss of information increases

Engineering Contradiction:
ImprovetransparencyVSAvoidsystem complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The system implements feedback mechanisms by providing detailed analytics and reporting at the patient and physician level, tracking transfusion procedures and outcomes, and generating transparency through documented decision-making processes that feed back into continuous improvement and accountability

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS11935653B2Blood transfusion management using artificial intelligence analytics
Publication Date: 2024.03.19 UNIVERSITY HOSPITALS OF CLEVELAND CLEVELAND
  • US11935653B2 patent drawing
  • US11935653B2 patent drawing
  • US11935653B2 patent drawing

AI summary

Method and apparatus are described for a system that employs a change management algorithm to drive transfusion “appropriateness” by factoring evidenced-based knowledge and input from practitioners, where said algorithm may also ensure that a blood or blood product transfusion is provided to the right patient, that the blood/blood product is transfused at the right time, and that the procedure is completed for the right reason.