Air-Actuated Olfactometer for MRI Environments

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Solution Overview

Problem

Delivering controlled odor stimuli to subjects inside an MRI scanner is challenging due to the hostile magnetic environment and the need for stable, controllable airflow, which existing technologies fail to address effectively.

Innovation Solution

An MRI-compatible olfactometer system utilizing air-actuated valves, a non-magnetic odor box, and a nose piece, which uses compressed air to direct odorized breathable air to the subject, ensuring safe and precise odor delivery within the scanner suite.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional solenoid valves are used to control odor delivery, then precise stimulus control is achieved, but the system becomes incompatible with MRI scanner environments due to ferrous materials

Engineering Contradiction:
ImproveMRI compatibilityVSAvoidodor delivery control
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent replaces electromagnetic solenoid valves with a pneumatic valve system actuated by compressed air. This substitution eliminates ferrous materials incompatible with MRI scanners while maintaining precise control over odor delivery timing and flow rates through air pressure regulation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system uses compressed air as the actuating medium for valve control and odor delivery. The pneumatic system includes an air supply, flow meters, and air-actuated valves that open/close odor canister access without requiring electromagnetic components, ensuring full MRI compatibility while achieving millisecond-level stimulus control

Inventive Principle:
Principle #29Pneumatics and hydraulics

2Manufacturing precision

If fast-acting valves are used to achieve square-shaped odor pulses, then stimulus precision is improved, but residual odor contamination increases

Engineering Contradiction:
Improvestimulus timing precisionVSAvoidresidual odor contamination
Core Design Contradiction:
Manufacturing precisionVSObject-generated harmful factors

Solution Approach 1:

The system segments the airflow path into separate channels: a main odor-free air flow and a separate odor canister access path. This allows the odorized air to be rapidly introduced and then quickly isolated, enabling fast stimulus onset/offset while preventing residual odor contamination through dedicated cleaning flushes

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system implements a cleaning mechanism where odor-free air is used to flush and clear residual odor from the delivery system between stimuli. This discarding of contaminated air and replacement with fresh odor-free air minimizes carryover effects while maintaining fast stimulus presentation capabilities

Inventive Principle:
Principle #34Discarding and recovering

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise and safe delivery of odor stimuli with fast onset and offset, minimizing residual odor contamination and tactile cues, allowing for effective central processing studies of olfactory information.

Implementation Method 1

The valve may be actuated using compressed air to thereby direct the breathable air into the odor canister

Methodology Applied
Scientific EffectCompressed air actuation: Pressure Increase

Data Source

PatentUS8899095B2MRI compatible and air-actuated olfactometer
Publication Date: 2014.12.02 MONELL CHEMICAL SENSES CENTER
  • US8899095B2 patent drawing
  • US8899095B2 patent drawing
  • US8899095B2 patent drawing

AI summary

An olfactometer is disclosed. Such an olfactometer may include a control unit, an odor box, and a nose piece in communication with the odor box. The control unit may include a reservoir, and a compressor for supplying pressurized air to the reservoir. The odor box may include at least one compressed air actuated valve, and at least one odor canister in communication with the valve. A compressed air flow and a breathable air flow are both released from the reservoir and directed to the valve. The compressed air flow actuates the valve to thereby direct the breathable air to the odor canister to odorize the breathable air. The odorized breathable air is then directed to the nose piece.