Anti-Sticking ALD Coating for Medical Stent Shape Retention
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Solution Overview
Problem
Medical stents often fail to return to their original shape post-expansion due to stiction, leading to potential obstruction and increased risk of re-stenosis, which may necessitate open surgery and induce inflammatory responses.
Innovation Solution
A method involving the deposition of an anti-sticking atomic layer or molecular layer coating, such as TiC, TaC, or WC, on deformable tubular wire meshes to prevent self-sticking during expansion and contraction, ensuring the stent retains its original form and minimizes adherence to tissues.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the stent is compressed during manufacturing and then released, then the stent can be inserted through the stenosed area, but the stent may not return to its original shape due to stiction
Solution Approach 1:
A coating layer is applied as an intermediary between the stent wire mesh and the surrounding tissue/environment. This coating prevents direct contact and adhesion between the stent and external surfaces, enabling the stent to return to its original shape without stiction during insertion and expansion operations
Solution Approach 2:
The anti-sticking coating is applied to the stent wire mesh surfaces before the stent is compressed and inserted. This preliminary coating application ensures that when the stent is later expanded in the body, it can return to its original shape without experiencing stiction, as the coating is already in place to prevent adhesion
2Reliability
If the stent is expanded to maintain open flow, then blood flow is restored, but the stent may adhere to tissues causing inflammatory responses
Solution Approach 1:
The coating acts as a mediator between the stent and tissue, creating a barrier that prevents direct adhesion and the subsequent inflammatory response. The coating layer allows the stent to maintain open flow while preventing harmful tissue interaction
Solution Approach 2:
The coating converts the potentially harmful effect of stent-tissue contact into a beneficial non-sticking interface. By applying the coating, the stent can expand and maintain flow without causing the harmful inflammatory responses that would otherwise occur from direct tissue adhesion
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The anti-sticking coating allows the stent to maintain its original form, preventing obstruction and reducing inflammatory responses, thereby enhancing the effectiveness and longevity of the stent placement while minimizing the risk of re-stenosis.
Implementation Method 1
the stent does not return to its intended original shape due to stiction
Implementation Method 2
depositing an anti-sticking coating by ALD or MLD on surfaces of the wire mesh
Implementation Method 3
depositing an anti-sticking coating by ALD or MLD on surfaces of the wire mesh
Implementation Method 4
depositing an anti-sticking coating by ALD or MLD on surfaces of the wire mesh
Data Source
AI summary
A medical stent, including a squeezable and expandable tubular wire mesh and an anti-sticking atomic layer deposition coating deposited on surfaces of the wire mesh. A method for manufacturing a medical stent, including taking a squeezable and expandable (i.e., deformable) tubular wire mesh, and depositing an anti-sticking atomic layer deposition coating on surfaces of the wire mesh to prevent the wire mesh from being stuck with itself when expanding from a squeezed form to a fully expanded form.