Adjustable Alert Thresholds for Physiological Event Detection

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Solution Overview

Problem

Existing alert management systems for detecting worsening heart failure (WHF) events in congestive heart failure (CHF) patients suffer from fractured or perpetual alerts, leading to unnecessary healthcare resource consumption and ineffective event distinction.

Innovation Solution

A system and method for managing alerts using adjustable onset and reset thresholds to optimize alert issuance, ensuring that alerts satisfy specified characteristics such as frequency, duration, and timing, thereby improving the detection of WHF events.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If alert thresholds are set to be sensitive for detecting WHF events, then detection sensitivity is improved, but false positive rate increases leading to fractured alerts

Engineering Contradiction:
Improvedetection sensitivityVSAvoidfalse positive rate
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent applies dynamics by making the alert thresholds adjustable rather than fixed. The system dynamically adapts thresholds based on individual patient baselines and response patterns, allowing sensitivity to be optimized for each patient while reducing false positives through personalized calibration.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes parameters by adjusting alert thresholds based on patient-specific baselines and historical data. The system modifies threshold values dynamically to balance detection sensitivity with false positive reduction, transforming static thresholds into adaptive parameters that respond to individual patient characteristics.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If alert thresholds are set to be stringent to reduce false positives, then false positive rate decreases, but detection sensitivity is reduced leading to missed events

Engineering Contradiction:
Improvefalse positive rateVSAvoiddetection sensitivity
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The system dynamically adjusts thresholds based on patient-specific baselines rather than using fixed stringent values. This allows the system to maintain high reliability by reducing false positives while preserving detection sensitivity through personalized threshold calibration that adapts to each patient's normal variability.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent transforms static stringent thresholds into dynamic parameters that are customized for each patient. By changing threshold values based on individual patient data and response patterns, the system achieves both low false positive rates and high detection sensitivity simultaneously.

Inventive Principle:
Principle #35Parameter changes

3Loss of time

If frequent monitoring is implemented to improve event detection, then detection timeliness is improved, but healthcare resource consumption increases

Engineering Contradiction:
Improvedetection timelinessVSAvoidhealthcare resource consumption
Core Design Contradiction:
Loss of timeVSLoss of energy

Solution Approach 1:

The patent applies local quality by tailoring monitoring intensity to individual patient needs rather than applying uniform frequent monitoring to all patients. The system identifies patients at higher risk and directs intensive monitoring resources to them, while using less intensive monitoring for stable patients, thereby improving detection timeliness for those who need it most while conserving healthcare resources.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The system changes monitoring parameters dynamically based on patient status and risk stratification. By adjusting monitoring frequency and intensity according to individual patient characteristics and real-time data, the system achieves timely detection for high-risk patients while reducing unnecessary resource consumption for low-risk patients.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP3435847B1Alert management for physiological event detection
Publication Date: 2025.12.03 CARDIAC PACEMAKERS INC
  • EP3435847B1 patent drawingFigure 1
  • EP3435847B1 patent drawingFigure 2
  • EP3435847B1 patent drawingFigure 3

AI summary

Systems, devices, and methods for managing alerts associated with a target physiological event such as a worsening heart failure event are described. A system may detect one or more alert onsets using an onset threshold, and one or more corresponding alert terminations using a reset threshold. Alerts may be issued corresponding to the detected alert onsets and alert terminations. The system may compare the alerts to a specified alert characteristic, and iteratively adjust the onset or reset threshold until the alerts corresponding to the adjusted onset or reset threshold satisfy the specified alert characteristic. The adjusted onset and reset thresholds may be presented to a user or a process for detecting the target physiological event.