Algae Olive Leaf Dermatological Composition for Fungal Infections
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Solution Overview
Problem
Current dermatological compositions for treating fungal infections and other skin issues often have limited efficacy, moderate effects, or undesirable side effects, and may contain non-natural components.
Innovation Solution
A dermatological composition comprising extracts from algae origin, particularly Arthrospira platensis, and olive leaf origin, including hydroxytyrosol, which provides a synergistic effect against microorganisms, forming a physical barrier and exhibiting antimicrobial, antifungal, and anti-viral properties without toxicity to mammalian cells.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional dermatological compositions are used to treat fungal infections, then some antimicrobial effect is achieved, but the efficacy is limited and moderate at best
Solution Approach 1:
The patent combines algae extract and olive leaf extract in a single dermatological composition to achieve synergistic antimicrobial effects. The algae extract provides certain antimicrobial properties while the olive leaf extract contributes additional antimicrobial compounds, particularly hydroxytyrosol, creating a composition that is more effective than either extract alone against fungal infections.
Solution Approach 2:
The invention uses a composite formulation consisting of two natural extracts with complementary properties. The algae extract and olive leaf extract form a composite material that leverages the strengths of both components, resulting in enhanced reliability and productivity in treating fungal infections compared to conventional single-agent compositions.
2Productivity
If conventional dermatological compositions are used, then some treatment effect is achieved, but undesired side effects occur
Solution Approach 1:
The patent utilizes natural extracts from algae and olive leaves that provide therapeutic benefits without the harmful side effects associated with conventional pharmaceutical agents. The natural compounds in these extracts deliver antimicrobial activity while being biocompatible and free from the toxic side effects that plague many synthetic dermatological treatments.
Solution Approach 2:
The invention changes the fundamental parameter of composition from synthetic pharmaceutical agents to natural extracts. This parameter change transforms the safety profile from harmful side effects to benign natural compounds, while maintaining or enhancing treatment effectiveness through the synergistic combination of algae and olive leaf extracts.
3Ease of manufacture
If conventional compositions are used, then treatment is provided, but non-natural components are included which are less desired
Solution Approach 1:
The patent extracts active antimicrobial compounds naturally from algae and olive leaves, removing the need for synthetic pharmaceutical ingredients. By taking out the essential therapeutic components through natural extraction processes, the invention provides a composition that is free from non-natural components while maintaining manufacturability and treatment effectiveness.
Solution Approach 2:
The invention fundamentally changes the composition parameter from synthetic to natural origin. The dermatological composition is formulated entirely from natural extracts, eliminating non-natural components while preserving ease of manufacture through established extraction and formulation techniques for natural products.
4Reliability
If single extract compositions are used (either algae or olive leaf alone), then some antimicrobial activity is achieved, but effectiveness against certain microorganisms is insufficient
Solution Approach 1:
The combined algae and olive leaf extract composition achieves multi-functionality by effectively targeting multiple types of microorganisms including bacteria, fungi, and viruses. The algae extract provides activity against certain pathogens while the olive leaf extract contributes broad-spectrum antimicrobial properties, creating a universal composition that adapts to treat various dermatological infections.
Solution Approach 2:
By merging algae extract and olive leaf extract, the patent creates a composition with enhanced adaptability. The algae extract targets specific microorganisms while the olive leaf extract, particularly through hydroxytyrosol, provides activity against other pathogens, resulting in a versatile composition that effectively addresses a broad range of dermatological infections.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively treats and prevents fungal infections, such as athlete's foot and nail fungus, while being safe and free from side effects, and also aids in wound healing and acne treatment by creating a hostile environment for pathogens.
Implementation Method 1
forming a physical barrier
Implementation Method 2
exhibiting antimicrobial, antifungal, and anti-viral properties
Implementation Method 3
hydroxytyrosol appears to be more cytotoxic than oleuropein, thus more effective against bacteria
Implementation Method 4
the combination of the material of algae origin (especially including amongst others beneficial polypeptides) and the material of olive leaf origin (especially including the hydroxytyrosol having beneficial properties) provides a synergistic effect
Implementation Method 5
Fatty acids can help to bring back this barrier
Implementation Method 6
demonstrate unique skin barrier properties
Data Source
AI summary
The invention provides a dermatological composition comprising materials of algae origin (e.g. Arthrospira platensis) and olive leaf origin, the composition at least comprising a polypeptide and hydroxytyrosol. The composition is for use in the treatment and/or prevention of a dermatological microbial infection, e.g. nail fungus, Athlete's foot, wound, chickenpox, acne. The invention also provides an applicator device comprising such composition. Further, the invention provides a method for preparing such dermatological composition. Especially, the composition at least comprises a polypeptide and hydroxytyrosol.