Alkaline Drink Formulation for Statin Delivery
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Solution Overview
Problem
Current methods for managing blood pressure, such as statins and modulation of blood viscosity, have limitations in effectively reducing or maintaining blood pressure levels, particularly in the context of rising global hypertension prevalence and associated cardiovascular risks.
Innovation Solution
A stable alkaline drink formulation containing statins, optionally combined with CBD and THC, is developed to lower blood pressure and viscosity, utilizing a non-magnetic suspended agitation process to produce pH-stable alkaline water, which includes solubilizers and other ingredients to enhance bioavailability and efficacy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If statins are administered in traditional tablet or capsule forms, then blood pressure management is achieved, but patient compliance and accessibility are limited particularly for children and individuals with swallowing difficulties
Solution Approach 1:
The patent transforms statins from traditional solid tablet or capsule forms into a liquid beverage formulation. This parameter change in physical state enables easy consumption for children and individuals with swallowing difficulties while maintaining the therapeutic dosage and blood pressure management efficacy of the statin active ingredient.
Solution Approach 2:
The patent uses alkaline water as an intermediary vehicle to deliver statins in a liquid form. The alkaline water serves as a suitable medium that enhances the solubility and bioavailability of statins while providing a pleasant tasting beverage that improves patient acceptance and compliance compared to traditional bitter-tasting tablet formulations.
2Quantity of substance
If alkaline water is used as a vehicle for statins, then solubility and bioavailability are enhanced, but pH stability must be maintained to prevent degradation
Solution Approach 1:
The patent incorporates pH buffering agents into the alkaline water formulation beforehand to cushion against pH fluctuations. This preemptive measure ensures that the alkaline environment remains stable and within the optimal range for statin stability, preventing degradation while maintaining enhanced solubility and bioavailability throughout the shelf life of the beverage.
3Stress or pressure
If blood viscosity is reduced through modulation, then blood pressure is lowered, but the mechanism requires precise control to avoid adverse effects
Solution Approach 1:
The patent replaces complex mechanical or procedural methods for controlling blood viscosity with a chemical approach using alkaline water and statins. The alkaline environment and statin medication work together to naturally reduce blood viscosity and lower blood pressure through biochemical mechanisms, providing a more reliable and easier-to-control alternative to invasive or mechanically complex intervention methods.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The drink formulation effectively reduces blood pressure and viscosity, providing a practical and efficient means to manage hypertension and associated cardiovascular diseases, particularly in individuals where traditional tablet or capsule forms are impractical.
Implementation Method 1
means for causing circulatory motion of water entering the vessel sufficient to suspend the solid material within the body of water during passage of water through the vessel
Implementation Method 2
the vessel containing a body of water and a solid particulate or granular material comprising one or more elementary metals or oxides thereof capable of raising the pH of the water
Data Source
AI summary
A drink comprising in admixture stable alkaline water and a statin or a statin precursor, the pH of the water being from 8 to 10.5. The drink may include other ingredients including CBD or THC.