Alkaloid-Phenol Adducts for E-Cigarette Throat Comfort
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Solution Overview
Problem
E-cigarettes using nicotine salts in e-liquids and solid atomizing cartridges face issues such as irritating smells, throat discomfort, and poor suction experiences due to the use of free nicotine and organic acid nicotine salts, which can cause 'acidosis' and 'acid excess', and low nicotine concentration e-cigarettes lead to slow addiction satisfaction and weak throat sensation.
Innovation Solution
A reaction compound of alkaloid and phenol is formed through a chemical reaction, creating a combined state (R—PH—O—N—I) that eliminates the irritating smell of alkaloids and improves throat comfort and suction experience by using a combination of hydrocarbon, aromatic, and phenyl ring groups, with phenolic hydroxyl groups reacting with alkaloids to form a stable compound that balances aerosol and aroma.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If free nicotine is used in e-cigarettes, then nicotine delivery is efficient, but it causes irritating smell and throat discomfort
Solution Approach 1:
The patent introduces phenolic compounds as intermediaries that react with nicotine to form nicotine phenolic adducts. These adducts serve as a mediator between free nicotine and the user, maintaining nicotine delivery while eliminating the irritating properties through chemical modification.
Solution Approach 2:
The patent changes the chemical state of nicotine from free base form to phenolic adduct form through chemical reaction. This parameter change transforms nicotine's properties, reducing volatility and irritation while maintaining psychoactive effects, thereby resolving the contradiction between delivery efficiency and user comfort.
2Object-affected harmful factors
If organic acid nicotine salt is used in e-cigarettes, then throat sensation is improved, but it causes acidosis and acid excess in the human body
Solution Approach 1:
The patent uses phenolic compounds as an alternative intermediary to form nicotine adducts, replacing the traditional organic acid salts. This substitution maintains the throat-soothing benefits of salt formation while avoiding the harmful metabolic effects of organic acids on the body's acid-base balance.
3Object-affected harmful factors
If nicotine concentration is decreased in e-cigarettes, then addiction is reduced, but addiction satisfaction becomes slow and throat sensation weakens
Solution Approach 1:
The patent changes the chemical form of nicotine to phenolic adducts, which alters the delivery characteristics and user experience. This allows for adjusted nicotine concentrations while maintaining effective throat sensation and satisfaction through the unique properties of the phenolic-nicotine complex, potentially enabling lower concentrations with equivalent effect.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The reaction compound of alkaloid and phenol enhances the suction experience by eliminating irritation, balancing aerosol, and reducing 'acidosis' and 'acid excess' issues, providing a faster, more satisfying, and fragrant inhalation experience without the sour smell associated with nicotine salts.
Implementation Method 1
the phenolic hydroxyl can eliminate the original irritating smell of the alkaloid through the chemical reaction... R—PH—OH+N—I→R—PH—O—N—I
Data Source
AI summary
Disclosed are a reaction compound of alkaloid and phenol, an e-liquid, an atomizing cartridge and an electronic atomizer. A reactant alkaloid and a reactant phenol are added into a reaction vessel, and heated and stirred continuously at 40-300° C. for 0.1-6000 minutes to obtain the reaction compound of alkaloid and phenol. In this way, the reaction compound of alkaloid and phenol, the e-liquid and the atomizing cartridge better the original choking irritation of the alkaloid in the electronic atomizer, which is beneficial for the mouth inhalation, does not cause troubles such as “acidosis”, “acid excess” and “sour smell”, and can provide a faster, more pleasant and satisfying suction experience.