Ion-Selective Electrode with Alkoxysilyl-Bonded Crown Ether Coating
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Solution Overview
Problem
Conventional ion-sensitive membranes used in ion-selective electrodes suffer from insufficient durability when repeatedly used for monitoring ion concentrations in human body fluids.
Innovation Solution
An ion-selective electrode with an ion-sensitive layer containing a crown ether structure formed of repeating units with alkoxysilyl groups bonded to a solid surface, where the alkoxysilyl groups react to form siloxane bonds, enhancing durability and ion selectivity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional ion-sensitive membranes are used, then ion selectivity is achieved, but durability is insufficient when repeatedly used
Solution Approach 1:
The patent uses a composite structure combining a solid support (glass or plastic) with an ion-sensitive layer containing crown ether derivatives. This composite design allows the membrane to maintain ion selectivity while the solid support provides structural durability for repeated measurements, resolving the contradiction between selectivity and durability.
Solution Approach 2:
The ion-sensitive layer is formed as a thin film coating on the solid support. This thin film structure maintains the flexibility and ion-selective properties while the underlying solid support provides the mechanical strength and durability needed for repeated use, addressing the durability issue without compromising ion selectivity.
2Measurement precision
If ion-sensitive substance is mixed with plasticizer in membrane support, then ion selectivity is achieved, but structural stability deteriorates
Solution Approach 1:
The patent forms a thin film ion-sensitive layer on a rigid solid support rather than using a plasticized membrane. The thin film contains the ion-sensitive substance (crown ether derivative) while the solid support (glass or plastic) provides structural stability, eliminating the need for plasticizers that compromise structural integrity.
Solution Approach 2:
The membrane is designed as a composite with a solid support providing structural stability and an ion-sensitive layer providing selectivity. This composite structure separates the structural function (handled by solid support) from the selective function (handled by ion-sensitive layer), achieving both stability and precision simultaneously.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The electrode exhibits improved durability and retains ion selectivity, suitable for continuous monitoring of ion concentrations in human body fluids, with a production method that includes dissolving alkali metal salts in a compound with epoxy and alkoxysilyl groups to coat the solid surface.
Implementation Method 1
at least one of the alkoxysilyl groups of the crown ether structure reacts to be bonded to at least a part of the surface of the solid
Implementation Method 2
an ion-sensitive layer containing an ion-sensitive substance... the ion-sensitive substance has a crown ether structure
Data Source
AI summary
An ion-selective electrode includes: an ion-sensitive layer containing an ion-sensitive substance; and a solid, in which at least a part of a surface of the solid is coated with the ion-sensitive layer, the ion-sensitive substance has a crown ether structure formed of at least two or more repeating units represented by Formula (a):—CR1R2—CR3X—O— (a)where X is an organic group having an alkoxysilyl group at a terminal, R1, R2, and R3 are each a hydrogen atom or a hydrocarbon group, and R1 or R2 may be bonded to X, and at least one of the alkoxysilyl groups of the crown ether structure reacts to be bonded to at least a part of the surface of the solid.