Alpha-Mangostin Sunscreen Composition Broadening UV Protection
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Solution Overview
Problem
Current sunscreen agents, both inorganic and organic, have limitations such as skin irritation, phototoxicity, and inadequate broad-spectrum protection, failing to meet the demand for safe and effective sun protection.
Innovation Solution
A cosmetic composition combining α-mangostin with inorganic or organic sunscreen agents, enhancing UV protection by expanding the sun protection wavelength range and improving photostability, while ensuring skin safety and comfort.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If inorganic sunscreen agents (nanoscale TiO2 and ZnO) are used to physically block UV rays, then skin protection is achieved, but skin irritation and phototoxicity occur, and a heavy feel is produced that is unfavorable to skin metabolism
Solution Approach 1:
The patent combines multiple sunscreen agents (natural and synthetic, organic and inorganic) into a synergistic formulation. Specifically, it merges compounds like butyl methoxydibenzoylmethane, octyl salicylate, and natural extracts to achieve full-spectrum UV protection while reducing the concentration of each individual agent, thereby minimizing skin irritation and phototoxicity effects
Solution Approach 2:
The invention uses composite sunscreen formulations that integrate different types of UV filters with complementary absorption spectra. The composite system includes agents absorbing in UVA range (320-400 nm) and UVB range (290-320 nm), creating a material system that provides broad-spectrum protection with reduced side effects compared to single-agent formulations
2Object-affected harmful factors
If organic sunscreen agents are used to absorb UV rays through electronic energy level transition, then high transparency and good absorption effects are achieved, but skin irritation, inflammation, allergies, endocrine interference, genetic toxicity, and photoinstability occur
Solution Approach 1:
The patent merges organic UV absorbers with inorganic sunscreen agents and natural extracts in a synergistic formulation. This combination allows the organic agents to provide high transparency and good absorption while the other components reduce their concentration and mitigate their harmful effects including skin irritation, photoinstability, and endocrine interference
Solution Approach 2:
The invention optimizes the concentration parameters of organic sunscreen agents in the formulation, using them at lower levels where their UV absorption effectiveness is maintained through synergistic interactions, thereby reducing their photoinstability and toxicological effects while achieving the required protection levels
3Object-generated harmful factors
If natural sunscreen agents are used to provide mild sun protection and high safety, then skin safety is improved, but UV absorption capacity is relatively low and the UV absorption band is narrow resulting in low broad-spectrum sunscreen capacity
Solution Approach 1:
The patent combines natural sunscreen agents with synthetic organic and inorganic UV filters to create a synergistic system. The natural agents provide skin safety and mild protection while the synthetic components fill in the absorption gaps to achieve comprehensive broad-spectrum coverage across UVA and UVB ranges
Solution Approach 2:
The invention creates a multi-functional sunscreen formulation where natural extracts provide antioxidant and anti-inflammatory benefits alongside UV protection, while synthetic agents contribute specific wavelength absorption. The formulation serves multiple protective functions simultaneously, achieving both high safety and broad-spectrum efficacy
4Object-affected harmful factors
If the sun protection factor (SPF) is increased to provide greater UV protection, then the protection level is improved, but the amount of UV absorber added increases leading to higher risk of side effects
Solution Approach 1:
The patent uses synergistic combinations of multiple UV filters with different absorption characteristics. This allows the formulation to achieve high SPF values through the cumulative and interactive effects of several agents at optimized concentrations, rather than relying on large amounts of a single UV absorber, thereby reducing side effects while maintaining high protection levels
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The combination significantly enhances UVB and UVA protection, increases SPF and PFA values, and provides a non-irritating, safe, and aesthetically pleasing sunscreen solution.
Implementation Method 1
α-mangostin has anti-UV effects, and can eliminate sun damages such as redness and swelling, and pigmentation of the skin due to exposure to the blazing sun
Implementation Method 2
nanoscale titanium dioxide (TiO2) and zinc oxide (ZnO), which protect the skin in a manner of physical blocking by reflecting or scattering the UV rays in sunlight through inorganic particles
Implementation Method 3
nanoscale titanium dioxide (TiO2) and zinc oxide (ZnO), which protect the skin in a manner of physical blocking by reflecting or scattering the UV rays in sunlight through inorganic particles
Implementation Method 4
The sunscreen principle of such UV absorbers is that electrons at the ground state absorb photons and then transit to the excited state through the transition of electronic energy level, and then release energy in various ways such as emitting fluorescence, releasing heat energy or emitting phosphorescence, and finally return to the ground state
Implementation Method 5
release energy in various ways such as emitting fluorescence
Implementation Method 6
release energy in various ways such as emitting fluorescence, releasing heat energy or emitting phosphorescence
Data Source
AI summary
A cosmetic composition containing α-mangostin, and use thereof are disclosed. The cosmetic composition includes α-mangostin and a sunscreen agent. The α-mangostin is a pure α-mangostin or an α-mangostin-containing extract. The sunscreen agent is an inorganic sunscreen agent or an organic sunscreen agent. Herein, the inorganic sunscreen agent is one or more selected from a group of zinc oxide and titanium dioxide. The organic sunscreen agent is a sunscreen agent having a sun protection wavelength range that can be complementary to that of the α-mangostin or a sunscreen agent that is easily decomposed or easily oxidized under UV exposure. The organic sunscreen agent is one or more selected from a group of butyl methoxydibenzoylmethane, octocrilene, ethylhexyl salicylate, octyl salicylate, homosalate, ethylhexyl methoxycinnamate and terephthalylidene dicamphor sulfonic acid.