Alpha1-Blocker Eyedrops for Self-Administered Myopia Control

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Solution Overview

Problem

Existing treatments for myopia progression are complex and require medical intervention, limiting their accessibility and effectiveness for self-administration.

Innovation Solution

Development of eyedrops containing α1-blockers, such as bunazosin, prazosin, urapidil, silodosin, tamsulosin, doxazosin, terazosin, naftopidil, trimazosin, indoramin, alfuzosin, and corynanthine, or their pharmaceutically acceptable salts, which can be self-administered to suppress myopia progression.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing treatments for myopia progression are used, then myopia progression can be suppressed, but the treatment complexity increases and requires medical intervention

Engineering Contradiction:
Improvemyopia progression suppressionVSAvoidtreatment complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent enables patients to self-administer eyedrops containing alpha1-blockers at home without requiring medical intervention. The treatment system is designed for patient autonomy, where individuals can independently apply the medication to suppress myopia progression, eliminating the need for complex medical procedures or professional administration

Inventive Principle:
Principle #25Self-service

2Reliability

If existing treatments for myopia progression are used, then myopia progression can be suppressed, but the accessibility and ease of self-administration are limited

Engineering Contradiction:
Improvemyopia progression suppressionVSAvoidself-administration ease
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The invention provides a treatment system that patients can independently administer themselves through simple eyedrop application. The formulation is designed for easy self-application, allowing patients to suppress myopia progression without requiring medical facility visits or professional assistance, thereby significantly improving accessibility and ease of use

Inventive Principle:
Principle #25Self-service

3Ease of operation

If simple self-administration methods are used, then ease of operation improves, but the effectiveness in suppressing myopia progression may be reduced

Engineering Contradiction:
Improveself-administration easeVSAvoidmyopia progression suppression
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent utilizes alpha1-blockers, which are pharmacological agents that block alpha1-adrenergic receptors. By changing the chemical parameter of the treatment from complex medical procedures to simple pharmacological eyedrops, the invention achieves both ease of self-administration and effective suppression of myopia progression through the specific mechanism of alpha1-receptor antagonism

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20250222008A1Eyedrops containing an alpha1-blocker for inhibiting myopia progression
Publication Date: 2025.07.10 TSUBOTA LAB
  • US20250222008A1 patent drawing
  • US20250222008A1 patent drawing
  • US20250222008A1 patent drawing

AI summary

Eyedrops for suppressing myopia progression containing an α1-blocker. The α1-blocker is one or more substances selected from a group consisting of bunazosin, prazosin, urapidil, silodosin, tamsulosin, doxazosin, terazosin, naftopidil, trimazosin, indoramin, alfuzosin, moxisylyte, and corynanthine, or pharmaceutically acceptable salts thereof.