Amino Acid Composition for Brain Function Improvement

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Solution Overview

Problem

Current amino acid compositions are ineffective in reducing brain dysfunction and fatigue caused by mental stress and exercise, leading to cognitive decline and depression.

Innovation Solution

A composition containing tyrosine, serine, alanine, aspartic acid, and glutamic acid, optionally with hydroxyproline, tryptophan, and asparagine, in specific blending ratios, administered to improve brain function and reduce fatigue.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional amino acid compositions are used, then brain function may be maintained under normal conditions, but they are ineffective in reducing brain dysfunction and fatigue caused by mental stress and exercise

Engineering Contradiction:

Improveeffectiveness in reducing brain dysfunction and fatigueVSAvoidapplicability to stress and exercise conditions

Core Design Contradiction:

ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent changes the parameters of the amino acid composition by specifying precise blending ratios (tyrosine:serine:alanine:aspartic acid:glutamic acid = 1:0.5:0.5:0.5:0.5 to 1:1.5:1.5:1.5:1.5) and including optional components (hydroxyproline, tryptophan, asparagine) in defined amounts, thereby optimizing the composition's effectiveness in reducing brain dysfunction and fatigue under stress and exercise conditions

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite amino acid composition by combining multiple amino acids (tyrosine, serine, alanine, aspartic acid, glutamic acid, and optionally hydroxyproline, tryptophan, asparagine) in specific ratios, forming a synergistic mixture that enhances brain function and reduces fatigue more effectively than individual amino acids alone

Inventive Principle:

Principle #40Composite materials

2Reliability

If amino acid compositions are administered to improve brain function, then cognitive function may be maintained, but long-term safety and continuous ingestion capability are not fully established

Engineering Contradiction:

Improvelong-term safety for continuous ingestionVSAvoidduration of brain function improvement

Core Design Contradiction:

ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The composition utilizes amino acids that are naturally metabolized by the body through existing biochemical pathways, allowing the body to process and utilize the ingredients without requiring external intervention or raising safety concerns for long-term continuous ingestion

Inventive Principle:

Principle #25Self-service

Solution Approach 2:

The patent specifies precise blending ratios and appropriate dosage ranges (6 mg to 180 g per serving) that optimize both effectiveness and safety for long-term use, ensuring the composition can be continuously ingested without adverse effects while maintaining brain function improvement

Inventive Principle:

Principle #35Parameter changes

Data Source

PatentUS11045437B2Composition for improving brain function

Publication Date: 2021.06.29 AJINOMOTO CO INC

AI summary

Compositions comprising (A) tyrosine, serine, alanine, aspartic acid and glutamic acid as active ingredients are useful for improving brain function and recovering from or suppressing fatigue and are highly safe and permit continuous ingestion or administration.