Eutectic Amino Acid Cosmetic Composition for Low-Irritation Exfoliation
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Solution Overview
Problem
Existing cosmetic compositions using alpha-hydroxy acids (AHAs) cause skin irritation at low pH and have low skin permeability at weakly acidic or neutral pH, and eutectic mixtures are unstable under severe conditions.
Innovation Solution
A cosmetic composition containing a eutectic mixture of serine and arginine at a 2:1 molar ratio, with optional water, maintains skin permeability and stability under weakly acidic or neutral conditions, reducing irritation and preserving keratin exfoliation effects.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If AHA is used at low pH to achieve keratin exfoliation, then exfoliation effect is improved, but skin irritation increases
Solution Approach 1:
The patent changes the pH parameter from low pH (2-4) to neutral or weakly acidic pH (6-8) while maintaining keratin exfoliation effect through the use of amino acid eutectic mixture, thereby reducing skin irritation associated with low pH
Solution Approach 2:
The patent uses a composite material system consisting of amino acid eutectic mixture (combining multiple amino acids in specific ratios) to achieve keratin exfoliation without relying on low pH, thus resolving the contradiction between exfoliation efficacy and skin irritation
2Object-affected harmful factors
If AHA is used at neutral or weakly acidic pH to reduce irritation, then skin irritation is reduced, but skin permeability decreases
Solution Approach 1:
The patent optimizes the composition parameters of the amino acid eutectic mixture (specific ratios of different amino acids) to maintain high skin permeability at neutral or weakly acidic pH, overcoming the limitation of conventional AHA formulations
Solution Approach 2:
The amino acid eutectic mixture acts as an intermediary substance that facilitates skin permeability at neutral pH, enabling active ingredients to penetrate skin effectively without requiring low pH conditions
3Speed
If conventional eutectic mixture is used in cosmetic formulation, then skin permeability is improved, but formulation stability deteriorates under severe conditions
Solution Approach 1:
The patent develops a composite amino acid eutectic mixture with optimized composition that maintains formulation stability under severe conditions (temperature variation, storage time) while preserving skin permeability benefits
Solution Approach 2:
The patent applies different amino acid ratios in different regions of the formulation or uses specific amino acid combinations that provide localized stability enhancement while maintaining overall formulation performance
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The eutectic mixture enhances skin permeability and keratin exfoliation effects while maintaining stability under severe conditions, reducing skin irritation and precipitation.
Implementation Method 1
the eutectic phenomenon is a phenomenon in which the melting point drops while two or more materials are mixed, so even though each component contained in the mixture shows a solid state at room temperature the mixture may become an anhydrous solution rather than a solid crystal
Implementation Method 2
which is due to Van der Waals interactions or hydrogen bonding between the components
Implementation Method 3
which is due to Van der Waals interactions or hydrogen bonding between the components
Data Source
Figure 1A~3(B)
Figure 4a(A)~4b(E)
Figure 5(A)~5(C)
AI summary
The present invention relates to a cosmetic composition comprising a eutectic mixture containing: an amino acid, an alpha-hydroxy acid, and water; or two types of amino acids. The cosmetic comprises either an amino acid and an alpha-hydroxy acid or two types of amino acids in the form of a eutectic mixture. Thus, a cosmetic composition with excellent skin penetration effect even under weakly acidic or neutral pH conditions, which causes less irritation, can be provided, wherein the cosmetic composition provides excellent keratin exfoliation, reduces the number of pores, enhances skin elasticity, and promotes skin regeneration while having excellent low-temperature stability.