Amino Acid Derivative Skin Compositions for Anti-Aging

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Solution Overview

Problem

There is a need for topical cosmetic compositions that effectively address dermatological signs of aging, such as fine lines, wrinkles, and sagging skin, without the limitations of low natural plant material availability and undesirable side effects, particularly for chronologically, hormonally, or photo-aged skin.

Innovation Solution

A topical cosmetic composition containing amino acid derivatives like L-theanine, S-Methyl-L-Cysteine, and S-Phenyl-L-Cysteine, which increase the expression of genes associated with the dermal-epidermal junction, cell-cell cohesion, and skin mechanical properties, thereby improving skin texture and appearance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If natural plant material is used as active ingredient, then the composition provides anti-aging benefits, but the natural plant material is present at low levels requiring large amounts to be processed

Engineering Contradiction:
Improveanti-aging efficacyVSAvoidamount of plant material required
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent extracts the active anti-aging components from natural plant material through processing to create concentrated compositions. This extraction process isolates the beneficial compounds (such as amino acid derivatives) from the bulk plant material, providing high efficacy at low concentrations and resolving the contradiction between needing anti-aging benefits and the large quantities of raw material required.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the concentration parameter of active ingredients by using highly processed and concentrated forms of plant-derived compounds. Instead of using crude extracts requiring large amounts, the invention employs purified and concentrated active components that deliver the same or better anti-aging effects at much lower concentrations, thus resolving the quantity versus efficacy contradiction.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If larger amounts of plant material are processed, then desired quantities of actives are obtained, but availability and difficulty of obtaining such materials increase

Engineering Contradiction:
Improvequantity of active ingredientVSAvoidavailability of plant material
Core Design Contradiction:
Quantity of substanceVSEase of manufacture

Solution Approach 1:

The patent creates synthetic or semi-synthetic copies of the active compounds found in rare plant materials. By replicating the molecular structure and biological activity of these natural compounds through chemical synthesis or fermentation, the invention provides an alternative source that is not limited by the availability of the original rare plant materials, thus resolving the contradiction between obtaining sufficient active ingredient quantity and the ease of manufacture.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent uses universal production methods such as fermentation and chemical synthesis that can produce the desired active ingredients regardless of the availability of specific plant sources. These multi-functional approaches allow the same active compounds to be produced through multiple pathways, ensuring supply continuity and ease of manufacture even when natural plant materials are scarce.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If conventional treatments are used to address aging skin, then dermatological signs of aging are treated, but undesirable side effects occur

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidside effects on skin
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses mild, naturally-derived amino acid derivatives that can gently stimulate collagen production and skin regeneration without causing the harsh side effects of conventional treatments. These compounds convert the potential harm of aggressive treatments into beneficial effects by providing a gentle yet effective approach to treating aging skin, improving treatment effectiveness while minimizing harmful side effects.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent employs amino acid derivatives as intermediary substances that mediate between the skin and the aging process. These compounds act as gentle mediators that stimulate natural skin repair mechanisms without causing the direct damage associated with conventional treatments, thus resolving the contradiction between treatment effectiveness and the presence of harmful side effects.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS8304455B2Compositions and methods of their use for improving the condition and appearance of skin
Publication Date: 2012.11.06 NEW AVON LLC

AI summary

The present invention relates to compositions and methods for treating, preventing and improving the condition and/or aesthetic appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, where the compositions include active agents which increase expression levels of genes associated with the dermatological signs of aging. The compositions of the invention are topically applied to the skin, or are delivered by directed means to a site in need thereof, once daily in an amount effective in improving the condition and/or aesthetic appearance of skin.