Positive Pressure Control in Automatic Analysis Reaction Area

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Solution Overview

Problem

Existing automatic analysis devices face challenges in preventing dust penetration into the reaction area, which affects detection sensitivity, particularly due to the limitations of airflow layer forming parts and vulnerability to dust ingress.

Innovation Solution

The device incorporates a first area with an openable/closable door for supplying consumables, a reaction area with controlled air pressure higher than the first area, and a means to manage air supply and exhaust based on the door's state, creating a positive pressure environment within the reaction area to minimize dust entry.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If an airflow layer forming part is used to prevent dust penetration, then dust blocking capability is improved, but the device size increases due to the large area required

Engineering Contradiction:
Improvedust penetration preventionVSAvoiddevice size
Core Design Contradiction:
Object-affected harmful factorsVSArea of stationary object

Solution Approach 1:

The patent applies pneumatic principles by using air supply means to create a positive pressure environment in the reaction area. Air is supplied through openings in the support structure, creating an airflow that prevents dust penetration without requiring large physical barriers. This resolves the contradiction by using fluid dynamics instead of large static structures.

Inventive Principle:
Principle #29Pneumatics and hydraulics

Solution Approach 2:

The patent changes the pressure parameter by making the reaction area have a higher pressure than the first area through controlled air supply. This pressure differential creates airflow that blocks dust penetration while avoiding the need for large-area physical barriers, thus resolving the size-dust protection contradiction.

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If an electrostatic eliminator is used to remove static electricity from the pipette tip, then dust adhesion prevention is improved, but dust penetration into the air intake remains vulnerable

Engineering Contradiction:
Improvedust adhesion preventionVSAvoiddust penetration resistance
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent uses pneumatic pressure control to create a positive pressure environment in the reaction area, which actively prevents dust penetration through airflow. This complements the electrostatic eliminator by addressing the air intake vulnerability that the electrostatic method alone cannot resolve.

Inventive Principle:
Principle #29Pneumatics and hydraulics

Solution Approach 2:

The patent applies preliminary anti-action by creating a positive pressure environment before dust can penetrate into the reaction area. The air supply means continuously maintains this pressure state, proactively preventing dust ingress rather than reacting to it after occurrence.

Inventive Principle:
Principle #9Preliminary anti-action

3Object-affected harmful factors

If the reaction area is sealed to prevent dust penetration, then dust blocking is improved, but accessibility for sample supply deteriorates

Engineering Contradiction:
Improvedust penetration preventionVSAvoidsample supply accessibility
Core Design Contradiction:
Object-affected harmful factorsVSEase of operation

Solution Approach 1:

The patent introduces an intermediary air flow system that mediates between the need for sealing and accessibility. The air supply means creates a protective pressure environment that allows the reaction area to remain effectively sealed while openings in the support structure enable sample and reagent supply without compromising dust protection.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration enhances detection sensitivity by effectively reducing dust penetration into the reaction area, thereby improving the accuracy of analyses in automatic analysis devices.

Implementation Method 1

a first air supply means or exhaust means for making the reaction area have a higher pressure than the first area

Methodology Applied
Scientific EffectPressure gradient: Pressure Gradient

Data Source

PatentEP3511719B1Automatic analysis device
Publication Date: 2023.08.02 HITACHI HIGH TECH CORP
  • EP3511719B1 patent drawingFigure 1
  • EP3511719B1 patent drawingFigure 2
  • EP3511719B1 patent drawingFigure 3

AI summary

In order to aspire to higher sensitivity in an automatic analysis device, it is important to prevent the mixing of dust and the like in a reaction part in which a sample and a reagent react. The present invention presents an automatic analysis device that is provided with a configuration for making the pressure inside a specific block in the device such as a reaction part, or inside the device become positive. By making the pressure become positive and forming an air flow that flows out from the inside of the reaction part or the device, it is possible to limit, to a certain amount or less, the amount of dust penetrating into the reaction part.