Analysis System With Partitioned Reaction Fields For Accurate Substance Detection

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Solution Overview

Problem

Existing analysis systems face challenges in accurately detecting subtle changes in emission color or emission spectrum shape due to interactions with target substances, and in generating a large amount of multidimensional data efficiently.

Innovation Solution

An analysis system comprising a plate with partitioned reaction fields for accommodating first and second components, where first signal information is acquired when only the first component is present, and second signal information is acquired after adding the second component, with machine learning used to analyze the difference between these signals.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If chemical reagents are disposed at high density to form reaction fields, then a large amount of multidimensional data can be generated, but chemical reagents may be eluted into solvent and blurred, increasing noise and variation

Engineering Contradiction:
Improvedata generation efficiencyVSAvoidanalysis accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The plate is divided into multiple partitioned reaction fields that are spatially separated. Each reaction field contains specific chemical reagents disposed at high density, but the partitions prevent elution and blurring between adjacent fields. This segmentation allows high-density reagent disposal for efficient data generation while maintaining measurement precision through physical isolation of each reaction zone.

Inventive Principle:
Principle #1Segmentation

2Reliability

If multidimensional data from multiple reactions is integrated, then feature amounts related to substance and phenomenon are enhanced, but the data becomes difficult for humans to understand

Engineering Contradiction:
Improvedata qualityVSAvoiddata interpretation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Machine learning algorithms serve as an intermediary between the complex multidimensional reaction data and human interpretation. The system collects enhanced feature amounts from multiple reactions integrated in the reaction fields, processes this complex data through machine learning models, and outputs meaningful results that are both scientifically rigorous and human-understandable.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If specific interaction probes are used to detect target substances, then information on specific substances can be obtained, but it requires matching probes with objects and selecting detection targets

Engineering Contradiction:
Improvedetection specificityVSAvoidprobe selection complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The reaction field plate system provides a universal platform that can detect multiple target substances simultaneously through integrated multiple reactions. Instead of requiring separate probe matching and selection procedures for each target, the system uses multiple chemical reagents disposed in partitioned fields that can collectively analyze various substances in a single experiment, reducing operational complexity while maintaining detection precision.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables accurate analysis of target substances by minimizing noise and variation, and efficiently generates a large amount of multidimensional data, improving data acquisition and analysis precision.

Implementation Method 1

when the reagents are mixed on the substrate, a reaction such as a more complicated chemical reaction, an ion reaction, a complex-forming reaction, an interaction, or energy transfer occurs

Methodology Applied
Scientific EffectChemical reaction: Chemical Bonding

Implementation Method 2

when the reagents are mixed on the substrate, a reaction such as a more complicated chemical reaction, an ion reaction, a complex-forming reaction, an interaction, or energy transfer occurs

Methodology Applied
Scientific EffectIon reaction: Ion Exchange

Implementation Method 3

when the reagents are mixed on the substrate, a reaction such as a more complicated chemical reaction, an ion reaction, a complex-forming reaction, an interaction, or energy transfer occurs

Methodology Applied
Scientific EffectComplex-forming reaction: Chemical Bonding

Implementation Method 4

when the reagents are mixed on the substrate, a reaction such as a more complicated chemical reaction, an ion reaction, a complex-forming reaction, an interaction, or energy transfer occurs

Methodology Applied
Scientific EffectEnergy transfer:

Implementation Method 5

information on light or color can be associated with a physical or quantum state change caused by reaction, interaction, complex formation, ionization, or the like of a substance

Methodology Applied
Scientific EffectLight detection: Absorption Spectroscopy

Implementation Method 6

information on light or color can be associated with a physical or quantum state change caused by reaction, interaction, complex formation, ionization, or the like of a substance

Methodology Applied
Scientific EffectColor measurement: Absorption Spectroscopy

Data Source

PatentUS20250163508A1Analysis system, plate, and analysis method
Publication Date: 2025.05.22 KONICA MINOLTA INC
  • US20250163508A1 patent drawing
  • US20250163508A1 patent drawing
  • US20250163508A1 patent drawing

AI summary

An object of the present invention is to provide an analysis system capable of analyzing a target substance more accurately, which includes: a plate including reaction fields for accommodating first and a second components, and partitioned at intervals; a signal information acquisition section to acquire first signal information from the plate and second signal information from the plate; and an analysis section for performing machine learning and analyzing a difference between the first signal information and the second signal information. At least two reaction fields respectively accommodate the first components having different compositions, and in at least one reaction field, reactions including interaction of the first component and/or the second component are caused.