Analyte Measurement Using Material Status Analysis

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Solution Overview

Problem

Existing methods for non-invasive measurement of analytes in body fluids, such as glucose concentrations in human skin, face challenges in improving accuracy and reducing measurement time.

Innovation Solution

The method involves a material status analyzing procedure that determines the current status of the material, including water content and other substances, to optimize the selection of analyte-characteristic-wavelengths and modulation frequencies used in the analyte measurement procedure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If material status analysis is performed to optimize measurement parameters, then measurement precision is improved, but measurement time increases

Engineering Contradiction:

Improveanalyte measurement accuracyVSAvoidmeasurement time

Core Design Contradiction:

Measurement precisionVSLoss of time

Solution Approach 1:

The material status analyzing procedure is performed before the analyte measurement procedure to determine optimal measurement parameters in advance. This preliminary analysis of water content and other material characteristics allows the system to pre-select the most suitable analyte-characteristic-wavelengths and modulation frequencies, thereby improving subsequent measurement precision without adding significant time overhead.

Inventive Principle:

Principle #10Preliminary action

Solution Approach 2:

The measurement parameters (wavelengths and modulation frequencies) are dynamically adjusted based on the real-time material status analysis results. The system adapts its measurement configuration to match the specific characteristics of the material being measured, optimizing the balance between measurement precision and measurement time for each individual measurement scenario.

Inventive Principle:

Principle #15Dynamics

2Measurement precision

If multiple analyte-characteristic-wavelengths are used simultaneously, then measurement precision is improved, but device complexity increases

Engineering Contradiction:

Improveanalyte concentration measurement accuracyVSAvoidmeasurement system complexity

Core Design Contradiction:

Measurement precisionVSDevice complexity

Solution Approach 1:

The system changes multiple parameters simultaneously (wavelengths and modulation frequencies) based on material status analysis results. By coordinating changes in both wavelength selection and modulation frequency, the system achieves enhanced measurement precision through multi-parameter optimization rather than simply increasing the number of wavelengths, thereby managing device complexity more effectively.

Inventive Principle:

Principle #35Parameter changes

3Productivity

If modulation frequency is increased, then productivity is improved, but measurement precision deteriorates

Engineering Contradiction:

Improvemeasurement speedVSAvoidanalyte measurement accuracy

Core Design Contradiction:

ProductivityVSMeasurement precision

Solution Approach 1:

The modulation frequency is dynamically selected based on the material status analysis results. The system determines the optimal modulation frequency that balances measurement speed and precision for the specific material being measured, rather than using a fixed high frequency that would compromise precision.

Inventive Principle:

Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the accuracy and efficiency of the analyte measurement by accounting for the material's status, allowing for more precise glucose concentration measurements in shorter times.

Implementation Method 1

the material is brought in thermal contact pressure transmitting contact with a measurement body, which thermal or pressure transmitting contact permits heat or pressure waves generated by absorption of excitation radiation in the material to be transferred to said measurement body

Methodology Applied

Scientific EffectThermal contact heat transfer: Conduction (thermal)

Implementation Method 2

a physical response of the measurement body, or of a component included therein, to heat or pressure waves received from said material upon absorption of said excitation radiation is detected

Methodology Applied

Scientific EffectAbsorption of electromagnetic radiation: Absorption (EM radiation)

Data Source

PatentEP4153967B1Method and apparatus for analyte measurement including material status analysis

Publication Date: 2025.05.14 DIAMONTECH GMBH

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AI summary

A method of analyzing a material (12) comprising at least one analyte, said method comprising a material status analyzing procedure (76), in which a present status of the material is analyzed, wherein based on a result of said material status analyzing procedure (76), at least one of a selection of analyte-characteristic-wavelengths used during an analyte measurement procedure (78), an absolute time or a relative time proportion of use of analyte-characteristic-wavelengths during said analyte measurement procedure (78), an individual excitation radiation intensity, or a relative weight given to the wavelengths in the analysis, a selection of analyte-characteristic-wavelengths to be used simultaneously during said analyte measurement procedure (78), and a selection of one or more main frequencies of the modulation of said excitation radiation (18) intensity to be used during said analyte measurement procedure (78) is determined.