Analyte Sensor Calibration for Time-Based Sensitivity Drift

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Solution Overview

Problem

Analyte sensors experience performance variations due to changes in sensitivity over time, including shelf and wear durations, leading to inaccurate analyte measurements.

Innovation Solution

Implement duration-based adjustments in analyte sensors to compensate for changes in sensitivity over time, using calibration parameters to maintain accuracy, including factory calibration and algorithms that adjust sensor data based on shelf and wear durations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If analyte sensors are used over extended periods, then more time is available for monitoring, but sensor sensitivity changes导致measurement accuracy deteriorates

Engineering Contradiction:

Improvesensor usage durationVSAvoidanalyte measurement accuracy

Core Design Contradiction:

Duration of action of moving objectVSMeasurement precision

Solution Approach 1:

The patent applies parameter changes by adjusting calibration parameters (slope and intercept) based on the sensor's age or duration of use. The system automatically modifies these parameters to compensate for sensitivity drift that occurs over time, thereby maintaining measurement accuracy throughout the sensor's operational lifespan without requiring manual recalibration.

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The system implements self-service through automatic calibration parameter adjustment. The sensor system autonomously monitors its own performance degradation and adjusts its calibration parameters accordingly, eliminating the need for user intervention or manual recalibration. This self-adjusting mechanism ensures continuous accuracy throughout the sensor's usage period.

Inventive Principle:

Principle #25Self-service

2Ease of operation

If factory calibration is used, then ease of operation is improved, but measurement precision deteriorates over time due to sensitivity changes

Engineering Contradiction:

Improvecalibration simplicityVSAvoidanalyte measurement accuracy

Core Design Contradiction:

Ease of operationVSMeasurement precision

Solution Approach 1:

The patent transforms the static factory calibration into a dynamic system that automatically adapts to changing sensor conditions. The calibration parameters are no longer fixed but are dynamically adjusted based on the sensor's age or performance characteristics, allowing the system to maintain accuracy throughout its operational life while preserving the simplicity of factory calibration.

Inventive Principle:

Principle #15Dynamics

3Measurement precision

If manual recalibration is performed frequently, then measurement precision is maintained, but ease of operation deteriorates due to user intervention requirements

Engineering Contradiction:

Improveanalyte measurement accuracyVSAvoiduser intervention frequency

Core Design Contradiction:

Measurement precisionVSEase of operation

Solution Approach 1:

Inventive Principle:

Principle #25Self-service

Data Source

PatentUS12575763B2Systems, devices, and methods with duration-based adjustment of sensor data

Publication Date: 2026.03.17 ABBOTT DIABETES CARE INC

AI summary

Embodiments that compensate for changes to sensor response characteristics (e.g., sensitivity) due to time durations are disclosed. The time durations can be the amount of time the sensor is in a post-manufacture packaged state prior to use, or the amount of time the sensor is in use. Sensor response changes due to other variables can also be compensated for.