Analyte Sensor Large Fill Port Segmented Chamber
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Solution Overview
Problem
Existing analyte sensors face challenges in efficiently handling small sample volumes due to limited sample fill port areas, leading to slower filling times and incomplete sample chamber filling.
Innovation Solution
The development of analyte sensors with large sample fill ports and supported tip protrusions, characterized by a high sample port area to volume ratio (Ap/Vc > 0.75 l/mm), which facilitates faster sample filling and complete chamber filling with small volumes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If the sample chamber volume is reduced to minimize sample volume requirements, then the sample port area to volume ratio decreases, but this leads to slower filling times and incomplete chamber filling
Solution Approach 1:
The invention changes the geometric parameters of the sample chamber by reducing its volume while simultaneously increasing the sample port area, achieving a high Ap/Vc ratio (>0.75 l/mm). This parameter optimization enables rapid filling of small sample volumes, resolving the contradiction between minimizing sample quantity and maintaining high filling speed.
2Quantity of substance
If the sample chamber volume is reduced to use smaller sample volumes, then the sample port area must be increased proportionally, but this increases the complexity of maintaining structural support
Solution Approach 1:
The invention segments the sample chamber structure into a head portion and a body portion, with the head portion having a larger cross-sectional area than the body portion. This segmentation allows the larger sample port area to be concentrated in the head portion, providing sufficient filling area while keeping the body portion compact and structurally simple.
Solution Approach 2:
The invention introduces a dimensional variation by creating a head portion with a larger cross-sectional area than the body portion. This dimensional change allows the sample port area to be increased without proportionally increasing the overall volume, maintaining structural simplicity while achieving high Ap/Vc ratio.
3Productivity
If the sample port area is increased to improve filling speed, then the sample chamber volume must be kept small, but this creates challenges in providing sufficient structural support
Solution Approach 1:
The sample chamber is segmented into a head portion and a body portion, with the head portion providing the larger sample port area for rapid filling. This segmentation concentrates the structural support requirements in the head portion while keeping the body portion compact, resolving the contradiction between large port area and sufficient structural support.
Solution Approach 2:
The invention applies local quality by making the head portion have a larger cross-sectional area than the body portion. This local expansion provides the necessary sample port area for high filling speed while the rest of the structure remains compact and structurally sound, maintaining overall strength.
Data Source
AI summary
The present disclosure provides small volume analyte sensors having large sample fill ports, supported analyte sensors, analyte sensors having supported tip protrusions and methods of making and using same.