Analyte Sensor Wire for Peritoneal Dialysis Catheter
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current dialysis methods, such as hemodialysis and peritoneal dialysis, are limited by their invasive procedures and lack of real-time monitoring capabilities, which restrict patient autonomy and understanding of peritoneal membrane function, leading to suboptimal treatment and quality of life for patients with renal dysfunction.
Innovation Solution
A device that can be connected to or inserted through a peritoneal dialysis catheter, featuring a sensor wire with an analyte sensor for real-time sensing and analysis, allowing concurrent dialysis and providing data for adjusting dialysis protocols based on analyte levels.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a sensor wire is inserted through the peritoneal catheter for real-time analyte measurement, then real-time monitoring capability is improved, but the risk of contamination and loss of sterility in the dialysis circuit increases
Solution Approach 1:
The device divides the catheter system into separate functional modules: the existing peritoneal catheter for fluid delivery and a separate sensor wire for analyte measurement. This segmentation allows the sensor to be introduced through the catheter lumen without compromising the sterility of the main dialysis circuit, as the sensor can be sterilized independently and inserted through the sterile barrier already provided by the catheter.
Solution Approach 2:
The peritoneal catheter itself serves as an intermediary sterile barrier through which the sensor wire is introduced. The catheter's existing sterile seal and connection mechanisms act as a mediator that allows the sensor to access the peritoneal cavity for real-time monitoring while maintaining the sterility of the dialysis fluid circuit.
2Ease of operation
If peritoneal dialysis treatment is performed with traditional methods, then treatment simplicity is maintained, but patient autonomy and quality of life are reduced due to lack of real-time monitoring
Solution Approach 1:
The sensor wire provides real-time feedback on analyte levels (such as glucose, creatinine, and other metabolites) in the peritoneal cavity. This feedback enables dynamic adjustment of dialysis treatment parameters and allows patients to monitor their own condition, thereby increasing patient autonomy and enabling personalized treatment protocols without complicating the overall treatment process.
Solution Approach 2:
Patients can independently monitor their own analyte levels through the sensor wire and use this information to make informed decisions about their treatment. The system empowers patients to self-manage their dialysis therapy by providing them with real-time data about their physiological state, increasing their autonomy while maintaining treatment simplicity.
3Stability of the object's composition
If the peritoneal membrane is considered as a fixed membrane based on traditional PET testing, then treatment protocol stability is maintained, but the ability to study and modify membrane function is lost
Solution Approach 1:
The sensor wire enables continuous real-time monitoring of analyte levels in the peritoneal cavity, providing an ongoing record of membrane function rather than discrete snapshots from PET testing. This continuous data stream allows researchers to study membrane characteristics dynamically and assess how pharmacological agents or other interventions modify membrane function over time, transforming the membrane from a static to a dynamically studyable system.
Solution Approach 2:
The system transitions from static, periodic assessment of membrane function (PET testing) to dynamic, real-time monitoring. The sensor wire captures temporal variations in analyte levels that reflect membrane function changes, enabling the study of membrane dynamics and the evaluation of interventions that aim to modify membrane characteristics.
Data Source
AI summary
The present invention relates to a device configured with an analyte sensor to measure analytes through an existing peritoneal dialysis catheter and to a method for using the device and to a method for changing of a dialysis protocol in a patient undergoing peritoneal dialysis using the device.