Analyte Test Device with Liquid Chamber for Sample Volume Control
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Solution Overview
Problem
Current rapid diagnosis devices are limited in their ability to detect multiple analytes simultaneously, and they often require sample dilution during collection, which can be inconvenient and may lead to issues with sample evaporation during transportation for secondary validation tests.
Innovation Solution
A device with a cover body containing a sample chamber and a liquid chamber that can move between locking and unlocking states, allowing for sample treatment and release into a testing chamber, which includes a testing element for analyte detection, and a method for using a treatment liquid to dissolve dried analytes for secondary validation tests.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If a single test strip is used for rapid diagnosis, then the operation is simple and results are obtained quickly, but only a single analyte can be detected at a time
Solution Approach 1:
The test device is divided into multiple independent test strips, each capable of detecting a specific analyte. The sample application pad is positioned to allow sample distribution across multiple test strips simultaneously, enabling parallel detection of multiple analytes while maintaining the simplicity and speed of single-strip operation
Solution Approach 2:
The sample application pad is designed with universal functionality to serve multiple test strips at once. It can distribute sample to different test strips simultaneously, making a single device capable of detecting multiple analytes through multiple test strips, thereby achieving multi-functionality without compromising operational simplicity
2Ease of operation
If samples are diluted during collection for testing, then the operation convenience is improved, but sample volume may be insufficient and evaporation issues occur during transportation
Solution Approach 1:
The sample application pad is pre-treated with hydrophilic substances and patterned with hydrophobic barriers before sample application. This preliminary preparation ensures that the sample is automatically distributed to multiple test strips in controlled amounts, eliminating the need for manual dilution during collection while ensuring sufficient sample volume reaches each test strip
Solution Approach 2:
The sample application pad acts as an intermediary between the collected sample and the multiple test strips. It performs automatic sample distribution and concentration regulation, serving as a mediator that ensures each test strip receives an appropriate amount of sample without requiring manual dilution, thus preventing both volume insufficiency and evaporation issues
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables convenient simultaneous detection of multiple analytes and prevents sample evaporation by mixing treatment liquid with the sample, ensuring sufficient volume for testing and facilitating secondary validation tests.
Implementation Method 1
a method for using a treatment liquid to dissolve dried analytes for secondary validation tests
Data Source
AI summary
The invention provides a device and method for testing an analyte in a liquid sample, and the device includes a cover body, where the cover body includes a sample chamber for accommodating a sample collector and a liquid chamber containing a sample treatment liquid. Thus, when an amount of the sample collected by the sample chamber is insufficient, liquid in the liquid chamber is released to increase the volume of the liquid sample. Alternatively, during secondary testing, the liquid sample reduced or even the liquid sample dried is allowed to be redissolved, thereby facilitating the secondary testing.