Non-Invasive Analyte Testing Using Structured Light and UV Spectra

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Solution Overview

Problem

Existing analyte testing technologies face challenges such as invasiveness, high cost, complexity, and inability to achieve real-time, portable, and accurate non-invasive measurements due to issues like mixed spectral signals and interference from skin components.

Innovation Solution

A method and system utilizing structured light and ultraviolet light to distinguish between areas with and without blood vessels, combined with fluorescence spectroscopy, to selectively obtain and analyze spectral data for analytes like glucose, using a trained model for accurate results without invasive methods.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If Raman spectroscopy is used for non-invasive analyte measurement, then measurement precision is improved, but device complexity and cost increase significantly

Engineering Contradiction:
Improveanalyte measurement accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts and eliminates the harmful spectral interference from skin components by separately measuring and subtracting the skin spectrum from the total spectrum. This allows the use of simpler absorption spectroscopy while achieving accurate analyte measurement without requiring complex Raman spectroscopy systems.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The measurement process is segmented into distinct steps: first measuring the skin component spectrum, then measuring the total spectrum including analyte, and finally separating the analyte signal by subtraction. This segmentation enables accurate measurement using simpler, more portable equipment.

Inventive Principle:
Principle #1Segmentation

2Ease of operation

If absorption spectroscopy is used for non-invasive testing, then ease of operation is improved, but measurement precision deteriorates due to mixed spectral signals

Engineering Contradiction:
Improvetesting simplicityVSAvoidanalyte detection accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent extracts the skin component spectrum as a separate measurement and removes it from the total spectrum through subtraction. This eliminates the harmful interference from skin components while maintaining the simplicity of absorption spectroscopy and preserving measurement precision.

Inventive Principle:
Principle #2Taking out (Extraction)

3Measurement precision

If multiple sensors and modules are used to collect biological signals, then measurement precision is improved, but device complexity and cost increase

Engineering Contradiction:
Improvetesting accuracyVSAvoidnumber of components
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple measurement functions into a single spectral measurement system. By measuring the total spectrum and the skin spectrum separately and then subtracting, the system achieves the accuracy of multiple sensors while using a single integrated device, reducing complexity and cost.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate, non-invasive, low-cost, and real-time analyte testing by distinguishing vessel locations, minimizing interference, and correlating spectral data directly with analyte concentrations, thus improving test accuracy and convenience.

Implementation Method 1

irradiating a first area by structural light within a first wavelength range, and imaging the first area, to obtain a first image of an imaging area

Methodology Applied
Scientific EffectOptical imaging: Light

Implementation Method 2

irradiating the first area by ultraviolet light within a second wavelength range, and imaging the first area, to obtain a second image of the imaging area

Methodology Applied
Scientific EffectFluorescence spectroscopy: Fluorescence

Data Source

PatentEP4681610A1Method and system for testing analyte, medium, and device
Publication Date: 2026.01.21 SENSURA PTE LTD
  • EP4681610A1 patent drawingFigure 1~2
  • EP4681610A1 patent drawingFigure 3~4
  • EP4681610A1 patent drawingFigure 5~6

AI summary

The present invention provides a method and a system for testing an analyte, a medium, and a device. The method includes: imaging: irradiating a first area by structural light within a first wavelength range, and imaging the first area, to obtain a first image of an imaging area; and irradiating the first area by ultraviolet light within a second wavelength range, and imaging the first area, to obtain a second image of the imaging area; spectral obtaining: obtaining depth information that indicate uneven distribution of the analyte in the imaging area from the first image; and based on the depth information, obtaining spectral data, at a desired position from the second image, that indicate uneven distribution of the analyte in the imaging area; and analyzing step: obtaining information about the analyte in the imaging area based on the obtained spectral data.