Analytical Method Parameter Segmentation for Chromatography

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Solution Overview

Problem

Current chromatographic analytical devices require pre-existing methods to be imported in a specific format, limiting the ability to develop new methods de novo and integrate diverse scientific knowledge effectively.

Innovation Solution

A method developer module that allows users to input analytical device method parameters, automatically generating complete methods using decision rules and enabling the transfer of multiple parameters from source documents, with integrated applications for improved integration and knowledge-based parameter selection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If pre-existing methods are imported in a specific format, then the system can operate with complete method packages, but the ability to develop new methods de novo is limited

Engineering Contradiction:

Improveability to develop new methodsVSAvoidmethod development complexity

Core Design Contradiction:

Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent segments a complete analytical method into individual parameters and setpoints that can be independently selected and imported. Users can now import specific instrument control parameters, sample injection parameters, and data analysis parameters separately rather than requiring complete pre-packaged methods, enabling flexible method development de novo while reducing the complexity of importing entire method packages.

Inventive Principle:

Principle #1Segmentation

2Ease of operation

If complete method packages are provided to users, then all instrument control setpoints are available together, but selective import of individual parameters is not possible

Engineering Contradiction:

Improveparameter import flexibilityVSAvoidmethod setup time

Core Design Contradiction:

Ease of operationVSLoss of time

Solution Approach 1:

The system divides complete method packages into discrete, selectable parameters including instrument control parameters, sample injection parameters, and data analysis parameters. This segmentation allows users to import only the specific parameters needed for their analysis rather than importing entire method packages, improving ease of operation and reducing method setup time.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The system prepares and stores complete method packages with all parameters pre-organized and categorized, allowing users to perform preliminary selection of needed parameters before actual import. This preliminary organization enables rapid selective import of individual parameters or groups of parameters, reducing the time required for method setup.

Inventive Principle:

Principle #10Preliminary action

3Adaptability or versatility

If pre-existing methods are required, then system operation is simplified, but integration of diverse scientific knowledge is limited

Engineering Contradiction:

Improveintegration ofscientific knowledgeVSAvoidmethod creation ease

Core Design Contradiction:

Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The system creates a universal parameter import interface that can accept and integrate diverse scientific knowledge from multiple sources including published methods, vendor protocols, and user-generated parameters. By establishing a common parameter structure that can accommodate different types of analytical methods and sources, the system enables flexible integration of diverse scientific knowledge while maintaining ease of method creation through standardized parameter selection.

Inventive Principle:

Principle #6Universality (Multi-functionality)

Data Source

PatentUS7475050B2Systems for developing analytical device methods

Publication Date: 2009.01.06 AGILENT TECHNOLOGIES INC

AI summary

Systems and processes for using the same for developing analytical device methods are provided. Also provided are computer program products for executing the subject processes.