Analytical Tool Stepped Portion Capillary Blood Pool
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing biosensors often inaccurately measure blood glucose levels due to sudden increases in oxidation current caused by blood moving beyond the air vent edge, leading to higher-than-actual glucose concentration readings.
Innovation Solution
An analytical tool with a substrate featuring a stepped portion, including a conductive dummy electrode and insulating layer, prevents the sample liquid from moving further, thereby maintaining the blood at the air vent edge and stabilizing the oxidation current measurement.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the capillary structure is used to move blood by capillary action, then the blood can be automatically introduced and retained in the capillary, but the blood may move beyond the air vent edge causing sudden increase in oxidation current and measurement error
Solution Approach 1:
The invention creates a stepped portion structure in advance that forms a blood pool at a specific position within the capillary. This preliminary structural arrangement ensures that when blood is introduced by capillary action, it automatically accumulates at the intended location and cannot move beyond the air vent edge, thereby preventing measurement errors caused by blood displacement.
2Reliability
If the reagent portion is dissolved by blood to establish liquid phase reaction system, then the electrochemical reaction can proceed, but the oxidation current suddenly increases when blood moves causing higher than actual glucose readings
Solution Approach 1:
The stepped portion structure acts as an intermediary element that mediates between the blood flow and the electrochemical reaction system. By creating a physical boundary (blood pool) at a specific location, it ensures that the blood remains stationary at the appropriate position, preventing the sudden movement that causes oxidation current spikes and measurement inaccuracies.
3Productivity
If the capillary allows free movement of blood, then the blood can reach the reaction area, but the blood may move beyond the air vent edge leading to measurement errors
Solution Approach 1:
The capillary is segmented into different functional zones by the stepped portion structure, creating distinct regions: a blood introduction zone, a blood pool accumulation zone, and a reaction zone. This segmentation allows blood to move efficiently to the reaction area while preventing it from moving beyond the air vent edge, thus maintaining both productivity and measurement precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution prevents sudden increases in oxidation current, ensuring accurate glucose level measurements by maintaining the blood within the capillary, thus improving analysis accuracy.
Implementation Method 1
a capillary 95 on the substrate 92. The capillary 95 is utilized for moving blood by capillary action
Data Source
AI summary
The present invention relates to an analytical tool (1) comprising a substrate (10), a capillary (13) which is formed on the substrate (10) and into which a sample liquid is to be loaded by movement of the sample liquid in the capillary. The substrate (10) is provided with a liquid movement preventer for preventing the sample liquid loaded into the capillary (13) from moving further. Preferably, the liquid movement preventer includes a stepped portion (18B) projecting from the substrate or a recess provided at the substrate.