Automatic Analyzer Precision Control Sample Management
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Solution Overview
Problem
Large-scale automatic analyzers require manual input of calibrators and precision control samples for calibration and precision control, which can disrupt the analysis of general samples if not properly managed, leading to potential measurement inaccuracies and increased operator burden.
Innovation Solution
An automatic analyzer system with a transferring mechanism and sample buffer unit that internally holds precision control samples, allowing for automatic analysis and calibration when predetermined conditions are met, such as low reagents or expired samples, eliminating the need for manual input and ensuring timely precision control.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If manual input of calibrators and precision control samples is required, then measurement precision can be maintained, but operator burden increases and analysis workflow may be disrupted
Solution Approach 1:
The system automatically manages precision control samples through internal storage and automated dispensing mechanisms. The analyzer independently performs calibration and precision control measurements without requiring manual operator intervention, thereby maintaining measurement precision while eliminating the burden of manual sample input
Solution Approach 2:
The system pre-stores precision control samples in an internal storage unit before analysis begins. This preliminary preparation allows the analyzer to automatically retrieve and use these samples during calibration and precision control phases, eliminating the need for operators to manually prepare and input these samples at the time of analysis
2Measurement precision
If manual input of precision control samples is required, then calibration and precision control can be performed, but analysis of general samples may be delayed
Solution Approach 1:
The automated system independently manages the timing and execution of precision control measurements, seamlessly integrating them into the overall analysis workflow without requiring operator intervention that would delay general sample analysis
Solution Approach 2:
The system maintains continuous operation by automatically performing precision control measurements between batches of general sample analysis. The internal storage and automated dispensing enable uninterrupted workflow, ensuring precision control is performed regularly without halting the analysis of general samples
3Adaptability or versatility
If calibrators and precision control samples are stored externally in sample racks, then flexibility is maintained, but operator intervention is required for proper positioning
Solution Approach 1:
The system features an internal storage unit that automatically stores and manages precision control samples. The analyzer independently retrieves these samples from internal storage and positions them in the sample handling mechanism, eliminating the need for operators to manually position samples in external racks while maintaining system flexibility
Solution Approach 2:
The system incorporates an internal storage unit within the analyzer body that contains precision control samples. This nested structure allows the samples to be stored compactly inside the analyzer and automatically accessed when needed, eliminating the need for external sample rack positioning while maintaining adaptability
Data Source
AI summary
An automatic analyzer for performing analysis of a precision control sample in response to an external factor to alleviate the burden on the operator and perform precision control at appropriate timing, thereby allowing automatic maintenance of the measurement precision. Analysis of a precision control sample is performed by creating an analysis request for the internally held precision control sample and then transferring the precision control sample in response to an external factor occurring, when a calibrator is inputted in the analyzer, the number of remaining reagents under analysis satisfies a predetermined condition (becomes zero or falls below a specified value), the date changes, a specified time runs out, the operator is changed, the number of analyzed samples exceeds a specified value, a specified time period has elapsed, a new reagent is registered, and a measurement failure is detected.


