Automatic Analyzer Precision Control Sample Management

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Solution Overview

Problem

Large-scale automatic analyzers require manual input of calibrators and precision control samples for calibration and precision control, which can disrupt the analysis of general samples if not properly managed, leading to potential measurement inaccuracies and increased operator burden.

Innovation Solution

An automatic analyzer system with a transferring mechanism and sample buffer unit that internally holds precision control samples, allowing for automatic analysis and calibration when predetermined conditions are met, such as low reagents or expired samples, eliminating the need for manual input and ensuring timely precision control.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual input of calibrators and precision control samples is required, then measurement precision can be maintained, but operator burden increases and analysis workflow may be disrupted

Engineering Contradiction:
Improvemeasurement precisionVSAvoidoperator burden
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system automatically manages precision control samples through internal storage and automated dispensing mechanisms. The analyzer independently performs calibration and precision control measurements without requiring manual operator intervention, thereby maintaining measurement precision while eliminating the burden of manual sample input

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system pre-stores precision control samples in an internal storage unit before analysis begins. This preliminary preparation allows the analyzer to automatically retrieve and use these samples during calibration and precision control phases, eliminating the need for operators to manually prepare and input these samples at the time of analysis

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If manual input of precision control samples is required, then calibration and precision control can be performed, but analysis of general samples may be delayed

Engineering Contradiction:
Improveprecision controlVSAvoidanalysis throughput
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The automated system independently manages the timing and execution of precision control measurements, seamlessly integrating them into the overall analysis workflow without requiring operator intervention that would delay general sample analysis

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system maintains continuous operation by automatically performing precision control measurements between batches of general sample analysis. The internal storage and automated dispensing enable uninterrupted workflow, ensuring precision control is performed regularly without halting the analysis of general samples

Inventive Principle:
Principle #20Continuity of useful action

3Adaptability or versatility

If calibrators and precision control samples are stored externally in sample racks, then flexibility is maintained, but operator intervention is required for proper positioning

Engineering Contradiction:
Improvesample rack flexibilityVSAvoidoperator intervention
Core Design Contradiction:
Adaptability or versatilityVSExtent of automation

Solution Approach 1:

The system features an internal storage unit that automatically stores and manages precision control samples. The analyzer independently retrieves these samples from internal storage and positions them in the sample handling mechanism, eliminating the need for operators to manually position samples in external racks while maintaining system flexibility

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system incorporates an internal storage unit within the analyzer body that contains precision control samples. This nested structure allows the samples to be stored compactly inside the analyzer and automatically accessed when needed, eliminating the need for external sample rack positioning while maintaining adaptability

Inventive Principle:
Principle #7Nested doll (Nesting)

Data Source

PatentUS8313695B2Automatic analyzer
Publication Date: 2012.11.20 HITACHI HIGH TECH CORP
  • US8313695B2 patent drawing
  • US8313695B2 patent drawing
  • US8313695B2 patent drawing

AI summary

An automatic analyzer for performing analysis of a precision control sample in response to an external factor to alleviate the burden on the operator and perform precision control at appropriate timing, thereby allowing automatic maintenance of the measurement precision. Analysis of a precision control sample is performed by creating an analysis request for the internally held precision control sample and then transferring the precision control sample in response to an external factor occurring, when a calibrator is inputted in the analyzer, the number of remaining reagents under analysis satisfies a predetermined condition (becomes zero or falls below a specified value), the date changes, a specified time runs out, the operator is changed, the number of analyzed samples exceeds a specified value, a specified time period has elapsed, a new reagent is registered, and a measurement failure is detected.