Automatic Analyzer Reagent Contamination Control
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Solution Overview
Problem
Automatic analyzing apparatuses face challenges in avoiding reagent contamination during multiple examination items, especially when the order of measurements cannot be changed, leading to decreased throughput due to the need for frequent detergent cleaning of the reagent dispensing probe.
Innovation Solution
The apparatus includes memory and processing circuitry that stores attribute information for reagents, allowing for the rearrangement of measurement orders and the determination of the necessity for probe cleaning based on this information, thereby potentially replacing detergent cleaning with reagent cleaning.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If the order of measurements is changed to avoid reagent contamination, then reagent contamination is avoided, but the measurement process becomes more complex and may not be applicable when order cannot be changed
Solution Approach 1:
The system pre-registers reagents that are sensitive to contamination and stores this information in advance. Based on this pre-prepared information, the measurement order is automatically optimized to prevent contamination before it occurs, rather than reacting to contamination after it happens.
Solution Approach 2:
The automatic analyzing apparatus autonomously determines and adjusts the measurement order based on registered reagent attributes without requiring external intervention. The system self-manages the optimization of measurement sequences to prevent reagent contamination.
2Reliability
If detergent cleaning is performed to avoid reagent contamination, then reagent contamination is avoided, but the examination throughput decreases due to cleaning cycles
Solution Approach 1:
The system pre-identifies reagents susceptible to contamination and pre-determines the optimal measurement order to avoid contamination. This preliminary planning eliminates the need for subsequent detergent cleaning cycles, maintaining high throughput while ensuring reliability.
Solution Approach 2:
The system changes the parameter of measurement order based on reagent attributes. By dynamically adjusting the sequence of measurements according to reagent sensitivity, the system prevents contamination without requiring time-consuming cleaning cycles, thus maintaining productivity.
3Productivity
If measurement order is optimized to avoid detergent cleaning, then throughput is improved, but reagent contamination may occur if optimization is insufficient
Solution Approach 1:
The system uses registered reagent information as feedback to continuously optimize the measurement order. By incorporating reagent attribute data into the ordering decision-making process, the system ensures both high throughput and reliable contamination avoidance.
Solution Approach 2:
The measurement order parameter is dynamically changed based on reagent attributes. This parameter optimization ensures that measurements are sequenced to prevent contamination while maintaining maximum throughput efficiency.
Data Source
AI summary
According to one embodiment, an automatic analyzing apparatus includes memory and processing circuitry. The memory stores attribute information indicating an attribute regarding cleaning set for any of a plurality of reagents. The processing circuitry performs at least one of rearrangement of a measurement order of a plurality of examination items in an examination and determination of necessity of probe cleaning by a detergent in the examination based on the attribute information.