Automatic Analyzer Sampling Window Adjustment for Magnetic Separation
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Solution Overview
Problem
Magnetic separation in automatic analyzers does not always progress evenly due to rotational motion and positional shifts of magnets, leading to fluctuations that degrade measurement accuracy.
Innovation Solution
An automatic analyzer is designed with a magnetic field generator, photometric unit, and decision unit that adjusts the sampling window based on spatial unevenness of magnetic separation, ensuring accurate measurement by correcting the use range of photometric signals.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If magnets are arranged to apply magnetic fields to reaction liquid in cuvette, then magnetic separation is achieved, but spatial unevenness occurs due to rotational motion and positional shifts of magnets
Solution Approach 1:
The patent applies dynamics by making the sampling window adjustable rather than fixed. The sampling window is dynamically adjusted based on the detected position of the cuvette in the magnetic field, allowing the measurement system to adapt to variations in magnetic field distribution caused by rotational motion and positional shifts of magnets.
Solution Approach 2:
The patent changes the parameter of the sampling window position and width based on detected magnetic field conditions. By varying these parameters according to the actual magnetic separation characteristics, the system maintains measurement accuracy despite spatial unevenness in the magnetic field distribution.
2Measurement precision
If fixed sampling window is used for measurement, then measurement process is simple, but measurement accuracy degrades when magnetic separation fluctuates
Solution Approach 1:
The patent implements feedback by detecting the position of the cuvette and the characteristics of magnetic separation, then using this information to adjust the sampling window. This closed-loop control ensures that the sampling window is optimized for each measurement condition, maintaining accuracy while managing complexity through intelligent control.
Solution Approach 2:
The system performs self-adjustment by automatically detecting magnetic separation characteristics and modifying the sampling window without external intervention. This self-service capability allows the system to maintain optimal measurement conditions autonomously, balancing accuracy with controlled complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution allows for accurate measurement item calculation without influence from magnetic separation fluctuations, enhancing reliability and precision in measurement results.
Implementation Method 1
a magnetic field generator configured to apply magnetic fields to a reaction liquid in a cuvette
Implementation Method 2
a photometric unit configured to detect the light generated by the light source unit and passed through the reaction liquid stored in the cuvette
Data Source
AI summary
According to one embodiment, an automatic analyzer includes a magnetic field generator, a photometric unit, a measurement unit, and a decision unit. The magnetic field generator causes magnetic separation in a reaction liquid stored in a cuvette by magnetic particles. The photometric unit includes a light source unit configured to generate light, and a detection unit configured to detect the light generated by the light source unit and generate an output signal corresponding to the detected light. The measurement unit measures a measurement item based on the output signal. The decision unit decides the use range of the output signal to be used to measure the measurement item in accordance with spatial unevenness of the magnetic separation by the magnetic field generator.