Model-Based Anatomical Segmentation via Boundary Point Selection

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Solution Overview

Problem

Automatic segmentation algorithms in medical images often produce erroneous results due to incorrect model selection, leading to sub-optimal segmentation and limited clinical value.

Innovation Solution

A system that allows users to interactively specify a limited set of boundary points in a medical image view to select the best-fitting segmentation model from a database based on a goodness-of-fit measure, reducing user effort and error.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automatic segmentation algorithms are used without user interaction, then productivity is improved, but reliability deteriorates due to erroneous model selection

Engineering Contradiction:
Improvesegmentation speedVSAvoidsegmentation accuracy
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system performs preliminary actions by providing multiple pre-defined segmentation models covering different anatomical variations before the actual segmentation process. The user selects from these pre-prepared models based on preliminary visual inspection, ensuring the correct model is chosen before automated segmentation begins, thus maintaining both speed and accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system enables semi-automated operation where the user performs a minimal self-service action (selecting boundary points) to guide the automated algorithm. This hybrid approach allows the system to serve itself through automated model fitting while incorporating minimal user input to ensure correct model selection, resolving the contradiction between automation and reliability.

Inventive Principle:
Principle #25Self-service

2Reliability

If manual segmentation is performed to ensure accuracy, then reliability is improved, but productivity deteriorates due to time-consuming operations

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidsegmentation speed
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

Instead of requiring complete manual segmentation, the system applies partial action by having the user specify only a limited set of boundary points (excessive action relative to minimal input, but insufficient for complete segmentation). This partial user input is then combined with automated model-based segmentation to produce complete accurate results, achieving both reliability and productivity.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The segmentation model acts as an intermediary between the user's minimal boundary point input and the final complete segmentation. The model bridges the gap by taking the partial user input and automatically generating the full segmentation, eliminating the need for complete manual delineation while ensuring accuracy through the model's anatomical knowledge.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If multiple segmentation models are available for different anatomical variations, then adaptability is improved, but device complexity increases due to model selection requirements

Engineering Contradiction:
Improveanatomical variability coverageVSAvoidmodel selection process
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system implements universality by creating a multi-functional framework where a single segmentation interface can handle multiple anatomical variations through different models. The user interacts with a unified system that automatically adapts to different anatomical cases by selecting from multiple models, eliminating the need for separate tools for each anatomical variation and reducing operational complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system manages complexity by changing parameters (model selection) based on user input rather than requiring structural changes. When anatomical variations are detected or specified by the user, the system adjusts which model parameters are applied, allowing adaptability to different anatomies through parameter adjustment rather than system reconfiguration.

Inventive Principle:
Principle #35Parameter changes

4Measurement precision

If complete manual boundary delineation is required for model selection, then measurement precision is improved, but loss of time increases

Engineering Contradiction:
Improveboundary point accuracyVSAvoiduser time for model selection
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary action by pre-defining multiple segmentation models that represent different anatomical variations before the user arrives. This preparation allows the user to select the appropriate model with minimal input (just a few boundary points) rather than having to manually delineate complete boundaries for model selection, significantly reducing time while maintaining precision through the pre-prepared models.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system applies partial action by requiring only a limited set of boundary points from the user (excessive relative to minimal input needed, but insufficient for complete segmentation) to perform model selection. This partial input is sufficient to identify the correct anatomical model, after which the automated system completes the segmentation, achieving high precision with minimal time investment from the user.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentEP3286728B1Model-based segmentation of an anatomical structure
Publication Date: 2023.08.30 KONINKLIJKE PHILIPS NV
  • EP3286728B1 patent drawingFigure 1
  • EP3286728B1 patent drawingFigure 2~2(iii)
  • EP3286728B1 patent drawingFigure 4(i)~4(iv)

AI summary

A system and method are provided for segmentation of an anatomical structure in which a user may interactively specify a limited set of boundary points of the anatomical structure in a view of a medical image. The set of boundary points may, on its own, be considered an insufficient segmentation of the anatomical structure in the medical image, but is rather used to select a segmentation model from a plurality of different segmentation models. The selection is based on a goodness-of-fit measure between the boundary points and each of the segmentation models. For example, a best-fitting model may be selected and used for segmentation of the anatomical structure. It is therefore not needed for the user to delineate the entire anatomical structure, which would be time consuming and ultimately error prone, nor is it needed for a segmentation algorithm to autonomously have to select a segmentation model, which may yield an erroneous selection.