Anchored Coronary Sinus Occlusion Catheter for Stable PICSO

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Solution Overview

Problem

Current PICSO catheters face issues with instability during occlusion, require time-consuming setup, and have low-fidelity pressure sensing, making them difficult to operate efficiently and effectively in coronary sinus procedures.

Innovation Solution

A catheter assembly with a steerable and deflectable distal end, an optical pressure sensor, and an anchoring device, an anchoring device for stable positioning, and a design that includes a smaller occlusion balloon and optical pressure sensing, eliminating the need for fluid-filled lines and reducing procedural time.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If an anchored catheter design is used, then stability during occlusion is improved, but device complexity increases

Engineering Contradiction:
Improvecatheter stabilityVSAvoiddevice complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The catheter is divided into distinct functional segments: a shaft with multiple lumens, a separate occlusion device (balloon) with diameter 5-15mm, and a proximal handle. This segmentation allows each component to be optimized independently while reducing overall complexity management.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The occlusion device is fixed to the distal tip of the shaft and nested within the catheter structure, while the anchoring mechanism integrates the occlusion device into the coronary sinus ostium. This nested arrangement provides stable positioning without requiring separate external anchoring systems.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Measurement precision

If optical pressure sensing is used, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvepressure measurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces traditional mechanical fluid-filled pressure sensing lines with an optical pressure sensor. This substitution eliminates the need for fluid-filled lumens connected to external pressure transducers, reducing setup time and improving measurement fidelity while integrating the sensing capability directly into the catheter structure.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Ease of operation

If a smaller occlusion balloon is used, then ease of operation is improved, but occlusion effectiveness may worsen

Engineering Contradiction:
Improveease of operationVSAvoidocclusion effectiveness
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The occlusion balloon diameter is specifically designed to be 5-15mm, optimizing the balance between ease of delivery and occlusion effectiveness. This parameter change allows the balloon to be small enough for straightforward catheter navigation while remaining large enough to effectively occlude the coronary sinus ostium and generate the required pressure rise throughout the coronary vasculature.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The new design provides reliable and fast intermittent occlusion with improved stability, reduced procedural time, and high-fidelity pressure measurement, enhancing the efficacy of PICSO procedures.

Implementation Method 1

means of measuring the pressure at the distal tip of the catheter assembly and distally to the occlusion device, preferably using an optical pressure sensor

Methodology Applied
Scientific EffectOptical sensing: Optical Fibre

Data Source

PatentEP4192571B1Anchored coronary sinus occlusion catheter with improved usability
Publication Date: 2025.11.12 CARDIAC IMPACT GMBH
  • EP4192571B1 patent drawingFigure 1~2
  • EP4192571B1 patent drawingFigure 3
  • EP4192571B1 patent drawingFigure 4

AI summary

The invention relates to a catheter assembly for the intermittent occlusion of the coronary sinus (CS, 60). The catheter assembly comprises a shaft (17, 126). The shaft (17, 126) has a plurality of lumens (7A, 7B, 35, 38, 40, 40A, 40B), a distal end (22) with a distal tip (20A, 20B, 20C), an occlusion device (24, 56, 142) fixed to the distal tip (20A, 20B, 20C) and operable through at least one of the plurality of lumens (7A, 7B, 35, 38, 40, 40A, 40B) and a proximal handle (10). The catheter assembly further having at least one of the following: - the occlusion device (24, 142) having a diameter of 5 20 mm and adapted to occlude the coronary sinus ostium, - means of measuring the pressure at the distal tip (20 a, 20B, 20C) of the catheter assembly and distally to the occlusion device (24, 142), preferably using an optical pressure sensor (28), - an anchoring device (30, 54, 65, 80, 90A, 122) for anchoring the occlusion device (24, 142) in a predefined position in the coronary sinus (CS, 60), preferably in the ostium, - the distal end (22) being deflectable/steerable with deflection being controlled by an actuator arranged at the proximal handle (10).