Anesthesia Recovery Control via End-Expiratory O2 Feedback

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Solution Overview

Problem

Current methods for controlling patient recovery from inhalation anesthesia face challenges in ensuring safe and controlled spontaneous ventilation, as they compromise oxygen delivery during the transition from mechanical to spontaneous breathing, risking hypoxia and inadequate oxygenation.

Innovation Solution

An automated anesthesia delivery system that includes a ventilator, gas mixer, vaporizer, and sensors to monitor and adjust oxygen and carbon dioxide concentrations, allowing for gradual reduction of anesthesia agent concentration and optimization of ventilation to match patient oxygenation demands, enabling safe and operator-independent recovery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If the ventilation is stopped or manually controlled to allow CO2 accumulation for stimulating spontaneous breathing, then the patient's ability to breathe spontaneously improves, but the oxygen delivery to the patient deteriorates, risking hypoxia

Engineering Contradiction:
Improvespontaneous breathing abilityVSAvoidoxygen delivery
Core Design Contradiction:
Adaptability or versatilityVSQuantity of substance

Solution Approach 1:

The system continuously monitors end-expiratory O2 and CO2 concentrations and uses this feedback to automatically adjust fresh gas flow rates and ventilation parameters. This closed-loop control ensures that CO2 accumulation occurs at safe rates while maintaining adequate oxygen delivery, resolving the contradiction between stimulating spontaneous breathing and preventing hypoxia

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system enables spontaneous breathing to develop naturally by allowing CO2 to accumulate to physiologically appropriate levels, while the automated control of oxygen delivery ensures the patient's oxygenation needs are met without continuous manual intervention. The patient's own respiratory drive serves the recovery process

Inventive Principle:
Principle #25Self-service

2Adaptability or versatility

If the anesthesia agent concentration is reduced to enable patient recovery, then the patient's spontaneous breathing capability improves, but the time required for complete agent clearance increases

Engineering Contradiction:
Improvespontaneous breathing capabilityVSAvoidrecovery time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The system prepares for spontaneous breathing by gradually reducing anesthesia agent concentration and simultaneously adjusting ventilation parameters and oxygen delivery in advance. This preliminary preparation allows the respiratory centers to adapt to changing gas concentrations before full spontaneous breathing is required, accelerating recovery while maintaining safety

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system dynamically adjusts ventilation rate, tidal volume, and fresh gas flow rates based on real-time monitoring of end-expiratory gas concentrations and patient spontaneous breaths. This dynamic adaptation optimizes the balance between clearing anesthesia agents and supporting spontaneous breathing throughout the recovery process

Inventive Principle:
Principle #15Dynamics

3Reliability

If automated control is implemented to manage oxygen and CO2 concentrations during recovery, then the safety and precision of oxygenation control improves, but the system complexity increases

Engineering Contradiction:
Improveoxygenation control safetyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The ventilator system integrates multiple functions into a single automated control platform that simultaneously manages ventilation, monitors end-expiratory gas concentrations, controls fresh gas mixing, and adjusts oxygen delivery. This multi-functionality achieves reliable automated oxygenation control without requiring separate complex systems for each function

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system ensures controlled and safe patient recovery by maintaining adequate oxygenation and reducing the risk of post-operative oxygenation problems, allowing for timely disconnection from ventilation support once spontaneous breathing is established.

Implementation Method 1

a sensor connected to the patient gas controller, for providing at least monitored expiratory O2 concentration for the patient

Methodology Applied
Scientific EffectGas concentration detection:

Implementation Method 2

a gas mixer and vaporizer for providing patient breathing gas, the gas mixer and vaporizer being connected to the ventilator

Methodology Applied
Scientific EffectGas mixing:

Implementation Method 3

a ventilator connected to the breathing device to provide a pressurized breathing gas

Methodology Applied
Scientific EffectPressure-driven gas flow: Pressure Gradient

Implementation Method 4

The anesthesia agent in the breathing gas mixture is ventilated into the lungs for diffusion to patient tissues

Methodology Applied
Scientific EffectDiffusion: Diffusion

Data Source

PatentEP3240599B1System for controlling patient recovery
Publication Date: 2021.06.09 GENERAL ELECTRIC CO
  • EP3240599B1 patent drawingFigure 1
  • EP3240599B1 patent drawingFigure 2

AI summary

Method and system for controlling patient recovery from anesthesia with an inhalation anesthesia agent, wherein the patient during the recovery is ventilated with a ventilator, the method comprising: - decreasing inhalation anesthesia agent concentration in the patient breathing gas to a level enabling patient spontaneous breathing, - monitoring the expiration of the patient to determine at least the expiratory O2 concentration, - determining a target level for the expiratory O2 level for the patient during recovery, - comparing the determined expiratory O2 concentration with the target level for the expiratory O2 level for the patient, and - controlling the O2 concentration in the ventilation gas to allow the expiratory O2 level for the patient to match the target level for the expiratory O2 concentration.