Variable-Porosity Aneurysm Implant for Neck Flow Restriction
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Solution Overview
Problem
Existing treatments for aneurysms, such as surgical clipping, coil embolization, and stent placement, do not effectively manage blood flow into and out of the aneurysm, and the vascular system, and do not promote endothelialization to strengthen the weakened vessel wall.
Innovation Solution
A medical implant with a frame and mesh component is designed to have varying porosity along its regions, allowing controlled blood flow and promoting endothelialization, featuring a tubular braid with a mesh component that restricts blood flow at the aneurysm neck while facilitating healing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a single mesh component with constant porosity is used, then the device structure is simple, but blood flow cannot be effectively controlled at different regions (aneurysm neck vs body)
Solution Approach 1:
The patent applies local quality by creating different porosity regions within the mesh component. The distal region has higher porosity to allow blood flow into the aneurysm body, while the proximal region has lower porosity to restrict flow at the aneurysm neck. This spatial variation in porosity enables differentiated blood flow control at different locations of the device.
Solution Approach 2:
The mesh component is segmented into multiple regions with distinct porosity characteristics. The device divides the uniform structure into functionally distinct zones (proximal low-porosity region and distal high-porosity region), allowing each segment to perform its specific function in blood flow management.
2Reliability
If blood flow into the aneurysm is restricted to promote endothelialization, then vessel wall strengthening is improved, but complete occlusion may not be achieved
Solution Approach 1:
The patent changes the porosity parameter spatially across the mesh component. By varying porosity from low in the proximal region to high in the distal region, the device creates a gradient that controls blood flow velocity and pressure, promoting endothelialization at the neck while maintaining controlled flow into the aneurysm body.
3Productivity
If the mesh component has high porosity throughout, then blood flow into the aneurysm is maintained, but endothelialization and healing are not promoted
Solution Approach 1:
The mesh component implements local quality by assigning different porosity values to different regions. The proximal region near the aneurysm neck has reduced porosity to promote endothelialization and healing, while the distal region maintains higher porosity to preserve blood flow into the aneurysm body.
Data Source
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AI summary
An implant can include a frame and a mesh component coupled to the frame. The mesh component can define a first porosity, and the frame can define a frame porosity. The combined porosity of the mesh component and the frame can restrict blood flow into the implant.